Double SHANK knockout highlights brain circuit’s social role
Mice missing the autism-linked SHANK2 and SHANK3 genes in their retrosplenial cortex have trouble distinguishing between novel and familiar mice.
Mice missing the autism-linked SHANK2 and SHANK3 genes in their retrosplenial cortex have trouble distinguishing between novel and familiar mice.
Interventions that moderate a need for ‘sameness’ may prevent anxiety traits.
The male sex bias in autism may in large part be a product of how common diagnostic tools measure traits in boys versus girls at a single point in time, according to a new study.
In this edition, researchers sink a purported link between cerebellar volume and autism and buoy a theory about measuring social behaviors.
Together, the neurons are part of the corticostriatal circuit, which has been implicated in autism.
Children who are diagnosed with autism before age 2 and a half years show more gains in their social skills than children who are diagnosed later.
Treating cognitive inflexibility — for example, by practicing problem-solving — might help ease anxiety and depression in autistic people.
Preliminary results suggested the treatment is no better than placebo at reducing the severity of core autism traits.
In this edition of Null and Noteworthy, tests of intranasal oxytocin and an Angelman syndrome treatment fail to see results.
Some types of restricted and repetitive behaviors become more prevalent among autistic children and teenagers over time, depending on their age and intellectual ability, whereas others decrease.