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Tag: repetitive behavior

October 2012
News

Fragile X syndrome can be treated in adulthood

by  /  19 October 2012

Activating the expression of FMR1, the gene mutated in fragile X syndrome, in adult mice reverses symptoms of the syndrome, according to a poster presented Monday at the Society for Neuroscience annual meeting in New Orleans.

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Cognitive test highlights flexibility deficits in autism

by  /  19 October 2012

A new cognitive test demonstrates the difficulties people with autism have with flexible thinking, according to a poster presented Wednesday at the Society for Neuroscience annual meeting in New Orleans.

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Study implicates ‘pleasure circuit’ in Angelman syndrome

by  /  18 October 2012

Mice that model Angelman syndrome, an autism-related disorder, are more motivated to earn rewards than controls are, according to unpublished results presented Wednesday at the 2012 Society for Neuroscience annual meeting in New Orleans.

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SHANK3 mice comparisons reveal array of differences

by  /  17 October 2012

Different mutations in the autism-linked SHANK3 gene lead to distinct glitches at the synapse, the junction between neurons, according to unpublished research presented Tuesday at the 2012 Society for Neuroscience annual meeting in New Orleans.

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Social molecule disrupted in autism mouse model

by  /  17 October 2012

Mice missing the autism-linked gene CNTNAP2 have broad defects in their oxytocin system, according to research presented Tuesday at the Society for Neuroscience annual meeting in New Orleans. Treatment with oxytocin alleviates social deficits in these mice.

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Autism mouse models show glitch in motor learning

by  /  16 October 2012

Two well-known mouse models of autism show abnormal reactions to an eye-blinking test that relies on the cerebellum, a brain region that helps integrate sensory information and plan movements. The unpublished results were presented in a poster Monday at the 2012 Society for Neuroscience annual meeting in New Orleans.

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Acetylcholine drug alleviates autism-like behaviors in mice

by  /  16 October 2012

A drug that mimics the neurotransmitter acetylcholine relieves repetitive behaviors in a mouse model of autism, according to a poster presented Monday at the Society for Neuroscience annual meeting in New Orleans.

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Children with autism get lost in time, imaging study says

by  /  15 October 2012

Children with autism recruit different brain regions than controls do when estimating how much time has gone by, according to unpublished research presented Monday at the 2012 Society for Neuroscience annual meeting in New Orleans.

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Mice with autism-linked deletion show unexpected deficits

by  /  15 October 2012

Mice lacking one copy of the autism-linked 16p11.2 chromosomal region are thin, deaf and show repetitive behaviors. They also have altered proportions of neurons in their brains, particularly those that express the chemical messenger dopamine. The unpublished results were presented Sunday at the 2012 Society for Neuroscience annual meeting in New Orleans.

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Mouse model links autism risk gene to mitochondria

by  /  11 October 2012

A new mouse model provides the first molecular link between the known autism risk gene PTEN and the mitochondrial dysfunction sometimes seen in the disorder. Mice with half the normal amount of PTEN protein in their brains have social deficits reminiscent of autism and faulty mitochondria, according to a study published 10 August in PLoS One.

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