Tag: regression

January 2013
Opinion / Viewpoint

Why crowdsourcing is not just for Wikipedia

by ,  /  22 January 2013

Crowdsourcing allows volunteers to become citizen scientists, archivists and journalists. Ventures such as the Interactive Autism Network can harness their power to advance autism research, say Paul Law and Cheryl Cohen.

2 Comments
October 2012
News

Mouse model links autism risk gene to mitochondria

by  /  11 October 2012

A new mouse model provides the first molecular link between the known autism risk gene PTEN and the mitochondrial dysfunction sometimes seen in the disorder. Mice with half the normal amount of PTEN protein in their brains have social deficits reminiscent of autism and faulty mitochondria, according to a study published 10 August in PLoS One.

2 Comments
September 2012
News

Genetics: Early seizures define Rett-like syndrome

by  /  28 September 2012

Mutations in the CDKL5 gene lead to developmental delay starting at birth, seizures that begin before 3 months of age, and subtly atypical facial features, according to a study published 8 August in the European Journal of Human Genetics.

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News

Regression may mark one-third of autism cases

by  /  27 September 2012

About one in three children with autism abruptly lose language, social or other developmental skills in their second year of life, according to a meta-analysis published 2 August in the Journal of Autism and Developmental Disorders.

8 Comments
News

Cognition and behavior: Regression marks autism syndrome

by  /  12 September 2012

Characteristic symptoms of Phelan-McDermid syndrome — a disorder caused by the loss of the 22q13.3 chromosomal region — may include bipolar disorder and a sudden loss of skills during adulthood, according a study published in June in Molecular Syndromology.

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August 2012
News

Genetics: Rare epilepsy syndromes share autism mutations

by  /  22 August 2012

Individuals with either of two rare forms of epilepsy have duplications or deletions that encompass genes implicated in autism and language impairment, according to a study published 27 June in Epilepsia.

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July 2012
News

Scientists track adult regression in autism-related syndrome

by  /  26 July 2012

Several scientists at the Phelan-McDermid Syndrome Foundation’s annual meeting focused on the wide range of symptoms, including a sudden loss of motor and cognitive skills, that seem to crop up in adults with the disorder.

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Opinion

Historic diagnosis

by  /  13 July 2012

Childhood disintegrative disorder may be the longest-lived of childhood psychiatric diagnoses. Austrian educator Theodor Heller described it more than 100 years ago, while working in a school for disabled children he had founded with his father. That reign may soon come to an end.

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News

Maternal antibodies may affect brain size in autism

by  /  12 July 2012

The action of certain maternal antibodies on the fetal brain may underlie the large brain size seen in some children with autism, according to preliminary findings from both monkey and human studies presented at a conference in Boston last week.

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April 2012
Opinion / Viewpoint

In defense of childhood disintegrative disorder

by ,  /  3 April 2012

Childhood disintegrative disorder represents a distinct entity within the autism spectrum and it should remain a separate diagnostic category, says Kevin Pelphrey.

20 Comments