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Spectrum: Autism Research News

Tag: Purkinje cells

July 2023
A slice of a cerebellum

Mutation in top autism-linked gene may alter eye reflex

by  /  7 July 2023

The discovery could help clinicians diagnose children who carry mutations in the gene, called SCN2A, and gauge their responses to potential therapies.

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September 2022
Illustration of hybrid objects: part light bulb, part lab vial, some in blue and some in red to signify null and replicated results.

Null and Noteworthy: Brain aging, oxytocin pathways, biomarker back-up

by  /  15 September 2022

Null and replicated results in this month’s newsletter tackle aging, a purported pathway for oxytocin’s effects on autistic people, and a possible autism biomarker.

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July 2022

Mouse study links dopamine in cerebellum to social behavior

by  /  6 July 2022

The signaling molecule’s social role in the ‘little brain’ involves Purkinje neurons in the Crus I and Crus II regions, a new study reveals.

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April 2022

Mice missing key clock gene show autism-like traits

by  /  28 April 2022

A new study is the first to link social, repetitive and motor behaviors to mutations in BMAL1, which regulates the body’s circadian rhythms.

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March 2022

Autism model mice develop typical social and motor behaviors after drug treatment

by  /  9 March 2022

The drug suppresses an overactive signaling pathway implicated in tuberous sclerosis complex.

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January 2021
lab mice

Mice with autism-related mutations show brain signaling imbalance

by  /  4 January 2021

Mutations in POGZ, a gene strongly linked to autism, lead to a signaling imbalance in multiple brain regions in mice, according to two new studies.

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March 2020
Illustration showing the human brain with neurons made out of flower shapes and the cerebellum highlighted in gold and yellow.

Brain’s motor hub plays unsung role in social skills, cognition

by  /  9 March 2020

Long known as the director of movement, the cerebellum may also coordinate social and cognitive abilities, including those central to autism.

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February 2018
Week of FebruaryFeb
19th
2018

Fake autism claim; knocking out anesthesia; haunting milestone and more

by  /  23 February 2018

Despite social media rumors, a British children’s television show does not cause autism; childhood anesthesia is not tied to autism risk; and an adult on the spectrum reaches a haunting milestone

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December 2017
four brains with the RCrusl section highlighted

Study of cerebellum’s role in autism homes in on ‘social’ region

by  /  18 December 2017

New evidence from both people and mice points to a part of the cerebellum that helps process social information as being critical in autism.

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February 2015

Timed cues create mini-cerebellum in culture

by  /  25 February 2015

Researchers can coax human stem cells to grow into layered structures that mimic the brain’s center for motor control, the cerebellum.

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