Autism and fragile X feature immune signatures
Scientists have identified distinct blood signatures of cytokines — proteins that control communication between cells of the immune system — in individuals with fragile X syndrome and autism.
Scientists have identified distinct blood signatures of cytokines — proteins that control communication between cells of the immune system — in individuals with fragile X syndrome and autism.
Young mouse models of fragile X syndrome show a significant lag in the development of synapses, the connections between neurons, according to a study published in Neuron. The findings suggest that a similar mistiming may be responsible for the sensory problems — such as hypersensitivity to touch and sound — sometimes seen in people with fragile X syndrome.
The proposed connection between premature birth and autism may be more complicated than it seems, according to a new report. Early birth may not cause classically defined autism but, rather, may predispose children to autism-like symptoms that are part of a larger syndrome, the researchers say.
A class of medications widely used during pregnancy to treat asthma and prevent early labor increases the baby’s risk of autism and other psychiatric disorders, according to a controversial review in the American Journal of Obstetrics and Gynecology.
Antibodies directed against the fetal brain are present in some mothers of children with autism, confirming previous findings and suggesting that the antibodies could be used as a marker for the disorder, according to unpublished research presented yesterday at the Society for Neuroscience meeting in Chicago.
Mice carrying an autism-associated mutation show impaired social interactions and dramatic changes in brain size when their immune systems are activated, according to research presented yesterday at a poster session at the Society for Neuroscience meeting in Chicago.
Tracy Bale, associate professor of neuroscience at the University of Pennsylvania, talks about what she calls her “big soapbox issue”: the fallacious idea of a true animal model for a human psychiatric disease — and the pitfalls of over-interpreting rodent behavior.
A team of British researchers has garnered some of the first genetic evidence supporting their theory that sex hormones play a role in the development of autism.
Women who take prenatal vitamins and eat cereal supplemented with folic acid in the early months of pregnancy are less likely to have children with autism compared with women who consume less folate, suggests preliminary data from a survey presented today at the Society for Neuroscience conference.
A new genetic study is lending support to the notion that immune system abnormalities and some forms of autism go hand in hand.