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Spectrum: Autism Research News

Tag: prefrontal cortex

January 2021

Two top autism genes may have a mechanism in common

by  /  13 January 2021

Mutations in two genes linked to autism and intellectual disability boost the immune response and cause synapse dysfunction.

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Senior man lying down in scanning machine.

Studies hint at effects of aging on autistic brains

by  /  12 January 2021

People with autism or autism traits may be especially vulnerable to brain aging and cognitive decline, two studies suggest.

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Heat map of mouse activity.

Circuit linking prefrontal cortex and brain’s relay station regulates social behavior in mice

by  /  11 January 2021

A set of neurons connecting the prefrontal cortex and the thalamus helps regulate social interactions in mice.

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September 2020
Brain images showing differences in signaling in autistic and normal brains.

Brain signal imbalance tracks with sex and with camouflaging autism traits

by  /  17 September 2020

Autistic men show a greater imbalance between excitatory and inhibitory signaling in the brain than autistic women do, which could explain sex differences in ‘camouflaging.’

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August 2020
Micrograph of neurons in mouse brain.

Inside scientists’ quest to map, modulate social circuits in autism

by  /  17 August 2020

A growing number of studies are revealing circuits that may underlie social challenges in autism — and how to fine-tune them.

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July 2020
An illustration of the brain shows the amydala highlighted in green among botanical forms that look like neurons.

Amygdala, the brain’s threat detector, has broad roles in autism

by  /  14 July 2020

The amygdala has long been a focus of autism research. But its exact role in the condition has been unclear.

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May 2020
Human brain with prefrontal cortex highlighted.

DNA differences may shape gene expression in the brain before birth

by  /  7 May 2020

Many genes in a brain region implicated in autism change expression patterns in late fetal development, depending on differences in neighboring DNA.

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April 2020
four brain views, seen from the side.

Brain anatomy differences in autism may vary by age, sex

by  /  13 April 2020

Several regions in the outer layer of the brain are thicker in children and young adults with autism than in their typical peers.

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March 2020

‘Social brain’ activity may not differ in some autistic people

by  /  16 March 2020

People with autism may have patterns of brain activity that are similar to those in typical people when interpreting social interactions.

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December 2019
Mouse sniffing the air

Mice with autism mutation may be indifferent to social scents

by  /  5 December 2019

Neurons in mice that lack an autism gene called CNTNAP2 do not differentiate well between social and nonsocial smells — an issue that seems to stem from haphazard neuronal firing.

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