Histone-modifying drug improves autism-like behaviors in mice
The experimental compound, called GSK-LSD1, enhances social preferences and reduces repetitive grooming in mice, according to a new study.
The experimental compound, called GSK-LSD1, enhances social preferences and reduces repetitive grooming in mice, according to a new study.
An atypical thalamus may underlie not only sensory issues in autism but also difficulties with social skills, attention and memory.
Mice missing the autism-linked gene SHANK3 use more neurons to engage in social behavior than control mice do, reflecting a more disorganized, less efficient brain signaling network.
A subset of brain cells signal when someone tries to infer another person’s thoughts, according to a new study.
A glowing protein tracks serotonin levels and location in the brains of living mice and could yield clues to the neurotransmitter’s role in autism.
Mutations in two genes linked to autism and intellectual disability boost the immune response and cause synapse dysfunction.
People with autism or autism traits may be especially vulnerable to brain aging and cognitive decline, two studies suggest.
A set of neurons connecting the prefrontal cortex and the thalamus helps regulate social interactions in mice.
Autistic men show a greater imbalance between excitatory and inhibitory signaling in the brain than autistic women do, which could explain sex differences in ‘camouflaging.’
A growing number of studies are revealing circuits that may underlie social challenges in autism — and how to fine-tune them.