Uncharted territory
Drug companies have been curiously reluctant to dive into research on therapies for autism. The chief of Pfizer’s new autism research unit explains why.
Drug companies have been curiously reluctant to dive into research on therapies for autism. The chief of Pfizer’s new autism research unit explains why.
Only people who already have social impairment benefit from oxytocin, researchers say.
If you believe the hype about oxytocin, it’s nothing short of a wonder drug: it can make you trust a stranger, enhance a mother’s bond with her child and, according to a study published earlier this year, improve social skills in individuals with autism. But look more closely, and there is ample cause for caution.
With robust training in developmental psychology and a techie’s fervor for new tools, Kevin Pelphrey is systematically investigating how the brain changes during development — starting in infants as young as 6 weeks old.
Researchers have pinpointed the brain circuits that underlie the vasopressin hormone’s role in regulating emotions.
A decade of research on the biology of autism, combined with a steady rise in diagnoses, has finally piqued the pharmaceutical industry’s interest in developing drugs for the disorder. Preliminary data from one small clinical trial already show positive results, and results from several others are expected early this summer.
Children with Williams syndrome — a rare genetic disorder that leads to mental retardation and overt friendliness — hold stereotypes based on gender, but not race, according to a report published in Current Biology. Because those with Williams syndrome don’t have social fear, the study suggests racial stereotypes are based partly on fear.
The older a grandmother was when she bore her grandchild’s mother, the greater the child’s risk of autism, according to a study published last month in PLoS One.
Neuroscientists have discovered a population of cells in the smell-perception area of the rat brain that express the hormone vasopressin. The study, published in Nature, begins to unpack the complicated molecular interactions of the hormone in the brain, which could lead to new autism treatments.
Scientists have been unable to replicate work showing an association between oxytocin receptor genes and autism.