A pH-sensitive red fluorescent molecule allows researchers to simultaneously monitor two different types of neuronal activity, according to a study published 27 May in Nature Neuroscience.
The heat produced by radio waves can interact with metallic nanoparticles bound to temperature-sensitive ion channels in cells, allowing researchers to remotely alter gene expression in live animals, according to a study published 4 May in Science. The technique could also be used to activate neuronal signals by manipulating calcium influx into neurons, the researchers say.
By manipulating the location of a protein that detects capsaicin, the molecule responsible for the burn in hot chili peppers, researchers can activate subpopulations of neurons and alter the behavior of mice. The results were published 20 March in Nature Communications.
A ten-year initiative announced last month by the Allen Institute for Brain Science aims to catalog the development, structure and function of neural circuits in the brain at an unprecedented level of detail.
Neurons lacking PTEN, an autism-associated gene also involved in cancer, are hyperconnected to both near and distant brain cells, according to a study published 1 February in The Journal of Neuroscience.
Male rhesus macaques show more interest in videos with social content, such as another monkey displaying aggression, than in videos of landscapes or other animals, according to a study published 26 October in PLoS One.
Researchers have engineered 20 mouse lines that allow them to manipulate genes in specific neuronal circuits. The resource, reported 22 September in Neuron, will allow researchers to better explore the role of interneurons, which dampen signals in the brain, in mouse models of autism.
Researchers can delay a monkey’s reaching movement by shining a beam of light into its brain, according to unpublished research presented at a poster session Sunday at the 2011 Society for Neuroscience annual meeting in Washington, D.C.
Researchers have engineered four new mouse lines that each show activation of a different subset of neurons in response to a blue light.
By zapping mouse brains with blue and yellow light beams, scientists have manipulated the animals’ social behaviors and bolstered a popular theory of what causes autism.