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Spectrum: Autism Research News

Tag: optogenetics

June 2022
A computer-rendered analysis of neurons

Autism-linked mutation disrupts brain circuit to change social behavior

by  /  24 June 2022

Therapies that target the circuit could boost social activity, new findings suggest.

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April 2022

Deep-learning tool tracks interacting animals in real time

by  /  27 April 2022

By coupling the tool — called SLEAP — with optogenetics, researchers can determine the neural circuits underlying social behaviors.

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March 2022

Switching neurons on and off to probe autism circuits

by  /  23 March 2022

A 3D optogenetics method can mimic natural rhythms of neural activity, rendering previously unanswerable questions amenable to inquiry — including questions about autism.

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Neurons lighting up yellow, green and red on blue.

Controlling neurons with ultrasound: Q&A with Sreekanth Chalasani

by  /  1 March 2022

The new method, called sonogenetics, noninvasively manipulates neural circuits in mice.

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September 2021
Scientist Ethan Scott takes aim with a bow and arrow in his backyard.

Beyond the Bench: A conversation with Ethan Scott

by  /  13 September 2021

Ethan Scott packs his lab with math, physics and computer science experts to decode sensory brain networks in zebrafish models of autism.

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July 2021
Ofer Yizhar in his lab, framed by rectangular window and a red background.

Beyond the Bench: A conversation with Ofer Yizhar

by  /  26 July 2021

When Yizhar isn’t building new tools to study the neural circuits underlying autism and other complex conditions, you can find him playing the piano, shooting photographs or taking long runs in the desert.

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image shows slice of a mouse brain with genes highlighted

Method tracks neuron paths, gene expression simultaneously

by  /  21 July 2021

A new technique can reveal where thousands of neurons send their axons — and measure the cells’ RNA levels for dozens of genes at the same time — in the mouse brain. It could be used to profile neural circuits underlying autism.

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New optogenetics technique minimizes thermal damage to neurons

by  /  8 July 2021

Thanks to a new engineered protein for optogenetics experiments, researchers can stimulate neurons with less light than usual and avoid damaging brain tissue.

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June 2021
wireless optogenetic device glowing green on mouse brain.

Wireless optogenetic devices sync neurons among mice

by  /  17 June 2021

Researchers say they can synchronize two new devices and control neurons across 256 freely moving animals at once to study social behaviors.

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May 2021
Researcher in red plaid shirt and blue nitrile gloves holds a lab mouse fitted with a fiber optic cannula, a needle-shaped glass piece that goes into the mouse's brain surrounded by a metal sleeve to which researchers attach a fiber optic patch cord.

How artificial intelligence is shaking up animal behavior studies in autism

by  /  24 May 2021

Next-generation machine-learning tools are poised to upend how scientists study behavior in animal models of autism — and not everyone is happy about it.

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