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Tag: optogenetics

July 2021
image shows slice of a mouse brain with genes highlighted
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Method tracks neuron paths, gene expression simultaneously

by  /  21 July 2021

A new technique can reveal where thousands of neurons send their axons — and measure the cells’ RNA levels for dozens of genes at the same time — in the mouse brain. It could be used to profile neural circuits underlying autism.

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New optogenetics technique minimizes thermal damage to neurons

by  /  8 July 2021

Thanks to a new engineered protein for optogenetics experiments, researchers can stimulate neurons with less light than usual and avoid damaging brain tissue.

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June 2021
wireless optogenetic device glowing green on mouse brain.
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Wireless optogenetic devices sync neurons among mice

by  /  17 June 2021

Researchers say they can synchronize two new devices and control neurons across 256 freely moving animals at once to study social behaviors.

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May 2021
Researcher in red plaid shirt and blue nitrile gloves holds a lab mouse fitted with a fiber optic cannula, a needle-shaped glass piece that goes into the mouse's brain surrounded by a metal sleeve to which researchers attach a fiber optic patch cord.
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How artificial intelligence is shaking up animal behavior studies in autism

by  /  24 May 2021

Next-generation machine-learning tools are poised to upend how scientists study behavior in animal models of autism — and not everyone is happy about it.

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February 2021
Mouse brains show different brain regions lighting up
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Ultrasound probe reveals brain circuit activity in living mice

by  /  18 February 2021

A new high-resolution imaging device tracks brain activity in awake mice, enabling researchers to map neural circuits across the entire brain.

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January 2021
Mouse brain slices shown in red
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Vasopressin relieves social deficits in an autism mouse model

by  /  25 January 2021

Mice missing a copy of MAGEL2 have trouble discerning between a familiar mouse and an unfamiliar one; treating them with the social hormone vasopressin reverses this deficit.

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Heat map of mouse activity.
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Circuit linking prefrontal cortex and brain’s relay station regulates social behavior in mice

by  /  11 January 2021

A set of neurons connecting the prefrontal cortex and the thalamus helps regulate social interactions in mice.

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September 2020
Neurons in a macaque cortex express parvalbumin in red.
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Virus-based method manipulates inhibitory neurons in brains

by  /  9 September 2020

A new viral tool can selectively control different types of neurons that dampen brain activity in rodents, monkeys and people.

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July 2020
Mouse with optpgenetic device in its head
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Wireless optogenetics device reveals new role for ‘cuddle hormone’

by  /  15 July 2020

A new wireless device switches oxytocin-producing neurons on and off in mice as they interact, showing the hormone’s effects depend on social context.

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May 2020
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Ultra-sensitive protein activates neurons in response to external light

by  /  27 May 2020

A new, minimally invasive technique allows researchers to activate neurons in the brains of mice and monkeys by using a light source located outside of the head.

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