Tag: OCD

June 2011
News

Molecular mechanisms: Mouse model supports role for SHANK3 in autism

by  /  3 June 2011

Mice with a mutation in SHANK3, a leading autism candidate gene, show moderate social defects, including less-than-normal interest in other mice. The findings, published 27 May in Cell, suggest that mutations in different sites on the gene can lead to different behaviors. This paper was retracted on 17 January 2013. Associate director of research Alan Packer discusses the implications of the retraction here.

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May 2011
News

Cognition and behavior: Drug enhances social learning

by  /  27 May 2011

A compound that activates a pathway related to learning and memory can enhance pair-bonding between prairie voles, according to a study published 7 April in Biological Psychiatry. Enhancing social learning — an individual’s response to social cues — during development could help treat autism.

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News

Cognition and behavior: Brain volume signals repetitive behavior

by  /  10 May 2011

Smaller-than-normal volume in several brain regions, including a region involved in relaying motor signals, could be a marker for repetitive behavior in 3-year-old children, according to a study published 7 April in Autism Research.

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April 2011
News

Genetics: New autism mouse reveals candidate gene

by  /  6 April 2011

A new mouse model for autism has obsessive behaviors and is less social and emits fewer vocalizations than controls, according to a study published 17 March in Behavioral Brain Research. These features could be be the result of much higher levels of FAM46, a gene of unknown function that may be involved in signaling between cells.

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January 2011
Opinion

Mind games

by  /  7 January 2011

As more drugs enter clinical trials for fragile X syndrome and soon, hopefully, for autism, the placebo effect will become an important consideration.

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July 2010
Opinion

Obsessive mice

by  /  21 July 2010

The biology of obsessive-compulsive disorder becomes even more baffling with the release of two new mouse models, each implicating a different type of brain cell.

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May 2010
Opinion

Multiple diagnoses

by  /  6 May 2010

A whopping 95 percent of children with autism have at least three other psychiatric disorders, and 74 percent have five or more, according to a study in the Journal of Autism and Developmental Disorders.

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February 2010
News

Dog pedigrees unearth genes for psychiatric disease

by  /  22 February 2010

Researchers are using dogs as models of psychiatric and behavioral conditions, including obsessive-compulsive disorder and autism.

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News

Variants in trust hormone receptor up the risk for autism

by  /  1 February 2010

Genetic variations that tweak the brain’s release of oxytocin — a hormone involved in social bonding and establishing trust — may increase the risk of developing autism or traits of the disorder, according to three new studies published in the past few months.

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News / Toolbox

Super-cool synapses

by  /  1 February 2010

A chilling new technique shows the intricate and coordinated activity of previously mysterious pieces of the synapse, the all-important junction between neurons that allows cells to talk to each other.

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