Tag: OCD

January 2012
News

Clinical research: Prozac may help adults with autism

by  /  25 January 2012

Fluoxetine, an antidepressant marketed as Prozac, may alleviate repetitive behaviors in adults with autism, according to a study published 2 December in the American Journal of Psychiatry.

2 Comments
August 2011
News

New focus on repetition, obsession in autism studies

by  /  18 August 2011

New studies of restricted and repetitive behaviors link autism to other disorders and may lead to more effective treatments.

7 Comments
July 2011
News

Cognition and behavior: SHANK1 mutant mice keep quiet

by  /  26 July 2011

Mice lacking SHANK1, a member of a family of autism-associated proteins, communicate less with their mothers and potential mates than controls do, according to a study published 9 June in PLoS One.

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News

Molecular mechanisms: Neurexin 1 forms flexible shape

by  /  12 July 2011

Neurexin 1, an autism-associated protein that functions at the junctions between neurons, has a flexible hinge that can toggle the protein between a more compact or a more accessible shape, a crystal structure published 8 June in Structure reveals.

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June 2011
News

Molecular mechanisms: Mouse model supports role for SHANK3 in autism

by  /  3 June 2011

Mice with a mutation in SHANK3, a leading autism candidate gene, show moderate social defects, including less-than-normal interest in other mice. The findings, published 27 May in Cell, suggest that mutations in different sites on the gene can lead to different behaviors. This paper was retracted on 17 January 2013. Associate director of research Alan Packer discusses the implications of the retraction here.

3 Comments
May 2011
News

Cognition and behavior: Drug enhances social learning

by  /  27 May 2011

A compound that activates a pathway related to learning and memory can enhance pair-bonding between prairie voles, according to a study published 7 April in Biological Psychiatry. Enhancing social learning — an individual’s response to social cues — during development could help treat autism.

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News

Cognition and behavior: Brain volume signals repetitive behavior

by  /  10 May 2011

Smaller-than-normal volume in several brain regions, including a region involved in relaying motor signals, could be a marker for repetitive behavior in 3-year-old children, according to a study published 7 April in Autism Research.

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April 2011
News

Genetics: New autism mouse reveals candidate gene

by  /  6 April 2011

A new mouse model for autism has obsessive behaviors and is less social and emits fewer vocalizations than controls, according to a study published 17 March in Behavioral Brain Research. These features could be be the result of much higher levels of FAM46, a gene of unknown function that may be involved in signaling between cells.

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January 2011
Opinion

Mind games

by  /  7 January 2011

As more drugs enter clinical trials for fragile X syndrome and soon, hopefully, for autism, the placebo effect will become an important consideration.

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July 2010
Opinion

Obsessive mice

by  /  21 July 2010

The biology of obsessive-compulsive disorder becomes even more baffling with the release of two new mouse models, each implicating a different type of brain cell.

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