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Spectrum: Autism Research News

Tag: neurotransmitters

April 2012

Chili pepper protein can alter behavior of mice

by  /  18 April 2012

By manipulating the location of a protein that detects capsaicin, the molecule responsible for the burn in hot chili peppers, researchers can activate subpopulations of neurons and alter the behavior of mice. The results were published 20 March in Nature Communications.

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March 2012

Molecular mechanisms: Autism protein forms aggregates

by  /  13 March 2012

DISC1, an autism-associated protein, can form large aggregates that deplete the amount of functional DISC1 in cells, according to a study published 14 February in Human Molecular Genetics.

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December 2011

Neurons made from stem cells reveal cellular flaws in autism

by  /  8 December 2011

Researchers have uncovered cellular abnormalities in Timothy syndrome by regenerating neurons from individuals with the rare autism-related disorder, according to a study published 27 November in Nature Medicine.

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November 2011

Researchers map microRNAs in autism brains

by  /  17 November 2011

Researchers have charted the expression of tiny pieces of RNA in postmortem brain tissue from people with autism, according to unpublished research presented Tuesday at the 2011 Society for Neuroscience annual meeting in Washington, D.C.

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Genetic studies probe sleep hormone’s role in autism

by  /  13 November 2011

A subset of people with autism have genetic and biochemical abnormalities in a sleep-related enzyme, according to research presented Friday at a satellite conference of the Society for Neuroscience annual meeting in Washington, D.C.

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October 2011

Growth factor improves autism symptoms in mice

by  /  19 October 2011

Mice lacking a copy of SHANK3, a gene associated with autism and intellectual disability, show marked improvements in brain signaling after being treated with insulin-like growth factor 1, according to unpublished findings presented Saturday at the International Congress of Human Genetics in Montreal, Canada.

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Molecular mechanisms: Neurons may be misdirected in autism

by  /  7 October 2011

The brains of individuals with autism express lower levels of proteins that direct neuronal growth compared with those of controls.

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September 2011

Clinical research: Oxytocin alleviates social anxiety

by  /  14 September 2011

Individuals with fragile X syndrome make slightly more eye contact in stressful social situations after taking oxytocin compared with placebo.

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Molecular mechanisms: Dopamine implicated in Rett syndrome

by  /  13 September 2011

Loss of MeCP2, the Rett syndrome gene, in neurons that release the chemical messenger dopamine may lead to the motor deficits associated with the syndrome.

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August 2011

Molecular mechanisms: MeCP2 loss ups signal strength

by  /  3 August 2011

A study using action potentials, the electrical impulses that trigger signaling, shows that neurons lacking MeCP2, the Rett syndrome protein, have stronger neuronal signals compared with controls, according to a study published in the July Journal of Neurophysiology.

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