Skip to main content

Spectrum: Autism Research News

Tag: neurogenesis

February 2023
Research image shows elevated expression of certain genes, shown in pink and green, along with expected gene expression, shown in blue.

Autism-linked MYT1L mutations prompt ‘identity crisis’ in budding brain cells

by  /  14 February 2023

Both human and mouse progenitor cells with the alterations struggle to become neurons and instead express genes that are typically active only in muscle or the heart.

Comments
Research image comparing neurons that lack the ZFP462 gene to wildtype neurons.

Autism-tied gene ZNF462 keeps developing neurons on track

by  /  1 February 2023

The gene, linked to a little-known condition called Weiss-Kruszka syndrome, prevents embryonic stem cells from deviating from their neuronal destiny.

Comments
October 2022
Image of a synthetic mouse embryo.

Lab-grown ‘embryoids’ offer new window into gene-trait relationships

by  /  26 October 2022

The developmental models have advantages over natural embryos and other synthetic models, such as organoids, but present technical and ethical challenges.

Comments