The new devices, which monitor neural activity from within blood vessels, show long-term stability in rats and could one day deliver electrical stimulation.
Spectrum: Autism Research News
Tag: neural networks
The tool connects to electrodes implanted in people with epilepsy or other brain conditions and can monitor and regulate neurons during everyday activities.
Conventional optogenetic manipulations to excite or inhibit neurons stop when the light switches off. A new approach makes the changes last.
Having an infection during pregnancy is tied to a small increase in the chances of having an autistic child, but the connection may not be causal.
Neurons with a faulty copy of SETD1A, a gene tied to autism and schizophrenia, show structural abnormalities and altered connectivity patterns.
The open-source device achieves subcellular resolution in a larger tissue volume than was possible with prior miniscopes, without impinging upon a mouse’s behavior.
Deep-learning algorithms can cut through some of the noise in brain imaging data collected across different sites.
The new technique can record hundreds of thousands of neurons firing nearly simultaneously across big swaths of brain tissue in living mice.
Mice missing the autism-linked gene SHANK3 use more neurons to engage in social behavior than control mice do, reflecting a more disorganized, less efficient brain signaling network.