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Tag: multiplex families

January 2012
News

Effect of paternal age seen in girls with autism

by  /  19 January 2012

Children, especially girls, with autism who have older fathers are more likely than those with younger fathers to be the only child with the disorder in their family, according to a new study published 16 December in Autism.

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December 2011
News

New scheme ramps up efforts to aggregate autism data

by  /  19 December 2011

The nation’s largest database of autism research is about to get even bigger, thanks to a partnership between the National Database for Autism Research, a repository of data from 25,000 participants, and the Autism Genetic Research Exchange, a database of 2,500 families.

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November 2011
News

Motor problems key feature of autism, family study suggests

by  /  21 November 2011

In families that have at least one child with autism, significant motor impairments crop up in most children with the disorder and hardly any of their unaffected siblings, according to a study published 19 October in Autism.

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October 2011
News

Clinical research: Parents share some autism traits

by  /  4 October 2011

Individuals who have multiple children with autism have more severe social and communication deficits than either controls or those who have only one child with autism.

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September 2011
News

Genetics: Protein that regulates serotonin linked to autism

by  /  27 September 2011

A protein that regulates the development of serotonin-producing neurons in the brain is associated with autism.

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News

Ambitious U.K. project set to sequence 10,000 genomes

by  /  15 September 2011

The largest and most ambitious genome-sequencing project to date aims to identify rare variants and study their association to disease traits in 10,000 people.

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August 2011
Opinion

Kissing cousins

by  /  5 August 2011

Marriages between first cousins are frowned upon in the U.S. and western Europe, but they are common throughout much of the world. A new study shows that these consanguineous unions can help researchers uncover genetic risk factors for neurodevelopmental diseases.

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January 2011
News

Genetics: Including gender improves autism genetics research

by  /  24 January 2011

Accounting for gender increases the power of family-wide studies linking genetic mutations with autism, according to a study published in December in Molecular Psychiatry. The researchers use this approach to identify two candidate genes for the disorder.

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December 2010
News

Genetics: Gene that controls methylation linked to autism

by  /  17 December 2010

A gene involved in epigenetics — regulation of gene expression by modifying DNA, but without altering the sequence — is associated with autism in families that have only one child with the disorder, according to a study published in November.

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November 2010
News

Genetics: Lower verbal intelligence in autism is inherited

by  /  17 November 2010

Better performance on intelligence tests that measure spatial rather than verbal ability is inherited in people with autism, according to a paper published online in October in Human Genetics.

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