Tracy Bale, associate professor of neuroscience at the University of Pennsylvania, talks about what she calls her “big soapbox issue”: the fallacious idea of a true animal model for a human psychiatric disease — and the pitfalls of over-interpreting rodent behavior.
Spectrum: Autism Research News
Tag: mouse models
Lithium treatment reverses some of the behavioral and brain-cell abnormalities in mouse models of fragile X syndrome ― an inherited form of mental retardation that includes learning deficits, aggressiveness, and social withdrawal ― according to research presented today at the Society for Neuroscience meeting.
Mice missing a copy of GAP43, a gene involved in the development of axons ― the thin strands that conduct electrical signals between nerve cells ― show biological and behavioral parallels to autism, according to unpublished research presented in a poster session today at the Society for Neuroscience conference.
A mouse model of neurofibromatosis ― a genetic neurodevelopmental disorder that leads to nerve tumors, memory problems and, often, autism ― exhibits deficits in social interaction and social learning, according to research presented in a poster session today at the Society for Neuroscience conference.
Even as I type this, thousands of neuroscientists are descending on Washington D.C. for an annual event that is almost beyond description. An estimated 36,000 people are expected to attend Neuroscience 2008, this yearʼs meeting of the Society for Neuroscience, hobnob, listen to lectures, present posters and down drinks at the many social events.