Cognition and behavior: Mouse model has autism-like brain
A well-studied mouse model of autism has a smaller-than-normal volume in several autism-associated brain regions.
A well-studied mouse model of autism has a smaller-than-normal volume in several autism-associated brain regions.
A new study describes a mutant mouse that, despite missing an autism-linked gene, doesn’t show any autism-like behaviors.
Mice lacking a copy of SHANK3, a gene associated with autism and intellectual disability, show marked improvements in brain signaling after being treated with insulin-like growth factor 1, according to unpublished findings presented Saturday at the International Congress of Human Genetics in Montreal, Canada.
Deleting one copy of TBX1, a gene located on the autism-linked chromosomal region 22q11.2, leads to social and communication deficits in mice.
Mouse pups with a duplication of GTF2I, a gene linked to Williams syndrome and autism, show extreme separation anxiety when separated from their mothers, according to unpublished findings presented Thursday at the International Congress of Human Genetics in Montreal, Canada.
Three common laboratory chemicals are all scientists need to create see-through brains ideal for visualizing complex neural circuits.
Two new genetic mouse models that debuted this week show that having too many or too few copies of certain genetic regions leads to an array of symptoms reminiscent of autism.
Researchers have engineered four new mouse lines that each show activation of a different subset of neurons in response to a blue light.
Mice lacking the autism-linked gene CNTNAP2 show many of the behaviors associated with the disorder, and exhibit brain circuit disruptions similar to those seen in people who carry mutations in the gene.
The male offspring of mice subjected to stress during pregnancy can transmit the effects to their own male pups.