In a video interview at the 2011 Society for Neuroscience annual meeting in Washington, D.C., Joseph Buxbaum discussed the importance of mice with mutations in SHANK3, a leading autism candidate gene.

A protein involved in the cascade of interactions at the junctions between neurons points to a potential therapy for fragile X syndrome, according to unpublished data presented at the 2011 Society for Neuroscience annual meeting in Washington, D.C.

Mice that have an excess of the Rett syndrome protein MeCP2 have biochemical and neuronal characteristics that are strikingly similar to those of mice that completely lack the protein, according to unpublished research described Sunday at the 2011 Society for Neuroscience annual meeting in Washington, D.C.

Mice lacking the autism risk gene SHANK2 show social deficits and are extremely hyperactive, according to unpublished research presented Saturday at the 2011 Society for Neuroscience annual meeting in Washington, D.C.

Deleting the Rett syndrome gene in a subset of neurons, instead of throughout the body, dramatically lowers the number of genes that are dysregulated in those neurons, according to results presented in a poster session Saturday at the 2011 Society for Neuroscience annual meeting in Washington, D.C.

Wenbao Gan describes the technique he has devised to track the development of neurons in live mouse brains.

After analyzing the brains and behaviors of mutant mice and screening genes in people with autism, researchers have pinpointed what they say is a new autism candidate gene: PRICKLE2. The unpublished work was presented Thursday in Washington, D.C.

A drug in trials for treating autism-related disorders can reverse memory problems and anxiety in adult mice lacking the schizophrenia gene DISC1 in some cells. The unpublished results were presented yesterday in Washington, D.C.

The Rett syndrome gene MeCP2 may subtly regulate the expression of genes across the genome by altering DNA structure.

Researchers have sequenced 17 laboratory mice and mapped 56.7 million single-base DNA variants in their genomes, according to a study published 15 September in Nature. A companion paper in the same issue identifies more than 700,000 structural variants, which are insertions, deletions or other modifications of DNA.