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Spectrum: Autism Research News

Tag: mouse models

October 2012

Researchers swing toward monkey models of autism

by  /  18 October 2012

Researchers in Japan have completed the first step in creating transgenic monkey models of autism, according to a poster presented Wednesday at the 2012 Society for Neuroscience annual meeting in New Orleans.

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SHANK3 mice comparisons reveal array of differences

by  /  17 October 2012

Different mutations in the autism-linked SHANK3 gene lead to distinct glitches at the synapse, the junction between neurons, according to unpublished research presented Tuesday at the 2012 Society for Neuroscience annual meeting in New Orleans.

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Video: Playing with light to manipulate the brain

by  /  17 October 2012

In a video interview at the 2012 Society for Neuroscience annual meeting, Edward Boyden discusses new tools his lab is developing to refine optogenetics techniques.

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Social molecule disrupted in autism mouse model

by  /  17 October 2012

Mice missing the autism-linked gene CNTNAP2 have broad defects in their oxytocin system, according to research presented Tuesday at the Society for Neuroscience annual meeting in New Orleans. Treatment with oxytocin alleviates social deficits in these mice.

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Statin pills in a blisterpack on a couch.

Cholesterol drug may treat fragile X syndrome

by  /  17 October 2012

A cholesterol-lowering drug called lovastatin prevents seizures in mice that model fragile X syndrome, according to a poster presented Sunday at the 2012 Society for Neuroscience annual meeting in New Orleans.

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Fragile X rats have trouble learning speech sounds

by  /  17 October 2012

Rats lacking FMR1, the gene mutated in people with fragile X syndrome, do not learn to discriminate between human speech sounds like control rats do, according to research presented Monday evening at the 2012 Society for Neuroscience annual meeting in New Orleans.

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Probiotic curbs autism features in mouse model

by  /  16 October 2012

Treatment with a single bacterial species curbs anxiety and repetitive behaviors and boosts vocalizations in a mouse model of autism, according to a poster presented Monday at the 2012 Society for Neuroscience annual meeting in New Orleans.

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Autism mouse models show glitch in motor learning

by  /  16 October 2012

Two well-known mouse models of autism show abnormal reactions to an eye-blinking test that relies on the cerebellum, a brain region that helps integrate sensory information and plan movements. The unpublished results were presented in a poster Monday at the 2012 Society for Neuroscience annual meeting in New Orleans.

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Acetylcholine drug alleviates autism-like behaviors in mice

by  /  16 October 2012

A drug that mimics the neurotransmitter acetylcholine relieves repetitive behaviors in a mouse model of autism, according to a poster presented Monday at the Society for Neuroscience annual meeting in New Orleans.

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A white mouse against a blue background.

Catalog of mice cries aids quest to find their meaning

by  /  15 October 2012

One research team is cataloging the vocalizations of 1,000 different mice, and a second group is creating a tool that will allow researchers to distinguish calls made by several mice as they interact, according to two posters presented Sunday at the 2012 Society for Neuroscience annual meeting in New Orleans.

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