Skip to main content

Spectrum: Autism Research News

Tag: mouse models

November 2020
Micrograph of nerve cells being targeted by CRISPR enzyme to activate the silenced gene in Angelman syndrome

Prenatal CRISPR therapy blocks Angelman syndrome traits in mice

by  /  9 November 2020

A gene-editing treatment shows long-lasting effects in a mouse model of Angelman syndrome, a genetic condition related to autism.

0 Comments
Fifteen different drugs commonly prescribed to people with autism created unique behavioral signatures in mice.

‘MoSeq’ identifies drug-specific behaviors in autism mouse model

by  /  2 November 2020

A tool that relies on video cameras and machine learning can identify mice that have mutations in a top autism gene by their behaviors. It also detects how a widely used autism drug affects their movements.

0 Comments
October 2020
White mouse grooming.

Nighttime light affects sleep, repetitive behaviors in autism mouse model

by  /  5 October 2020

Mice missing an autism gene groom themselves more than usual and have altered circadian rhythms after nighttime exposure to light.

0 Comments
September 2020
White lab mouse sitting in a gloved hand.

Silencing ‘poison exon’ eliminates deadly seizures in mice

by  /  24 September 2020

A new treatment curbs deadly seizures in a mouse model of Dravet syndrome, a severe form of epilepsy.

0 Comments
Illustration of a neuron on top of a marijuana leaf surrounded by psychadelic colors.

Cannabis and autism, explained

by  /  7 September 2020

Autistic people and their families are increasingly experimenting with marijuana to try to ease problems such as insomnia, epilepsy and chronic pain — and traits of autism. But there is little evidence for its safety or effectiveness.

0 Comments
Zebrafish embryos with various deformities.

CRISPR technique knocks down gene expression in animal embryos

by  /  2 September 2020

A new method that suppresses gene expression in the embryos of fish and mice may help researchers study autism genes in early development.

0 Comments
August 2020
Two mice side-by-side.

Drug improves social behaviors, oxytocin signaling in autism mouse model

by  /  31 August 2020

Mice missing the autism gene NLGN3 have altered social behaviors and brain responses to the hormone oxytocin, both of which improve after treatment with a drug that helps regulate protein production.

0 Comments
RNA, transcription

Antidote to ‘poison’ DNA may treat lethal form of epilepsy

by  /  26 August 2020

An experimental drug silences a DNA segment and seems to prevent seizures and death in a condition related to autism.

0 Comments
Fat in bloodstream visualized as yellow balls, floating near blood cells, macro view.

Blood lipid levels may be altered in some autistic people

by  /  10 August 2020

About 6.5 percent of autistic people in the United States also have dyslipidemia, a condition characterized by abnormal lipids levels in the blood.

0 Comments
July 2020
Person sleeping with EEG electrodes attached to head

Losing sleep: How researchers miss a key contributor to autism

by ,  /  16 July 2020

Doctors and scientists should consider sleep problems an integral part of autism and begin to study them in more rigorous ways.

0 Comments