Whole-genome sequencing data — which include information about mitochondrial DNA — offer clues to why mutations in the same gene can lead to autism or cancer.
Spectrum: Autism Research News
The in-depth approach shows mutations in the autism-linked gene disrupt neuronal growth and communication, as well as mitochondrial gene expression.
The DNA specific to mitochondria is difficult to access, but new methods place its secrets within reach.
Clues that problems with mitochondria contribute to autism have been accumulating for decades. In the past five years, a mutant mouse and a flurry of findings have energized the field.
These short reports from Spectrum journalists highlight some of the autism-related findings that caught our attention at the meeting this past week.
Mice with a mutation in their mitochondrial DNA show altered brain activity, repetitive behaviors and reduced sociability, according to a new study.
Gene therapies and the factors influencing autism traits top Spectrum’s list of the 10 most notable research findings we covered in 2020.
Plugging a leaky mitochondrial membrane may help fragile X neurons to mature and function more efficiently.
Some cases of anxiety, which often accompanies autism, may stem from a faulty immune system, a new study suggests — but some experts are skeptical.