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Spectrum: Autism Research News

Tag: microRNAs

October 2015

Male mice pass stress signatures down to their pups

by  /  19 October 2015

The pups of male mice exposed to stress show a muted response to stressful situations of their own, suggesting that environmental effects can last generations.

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January 2015

Method charts lifetime expression of DNA in brain

by  /  21 January 2015

A new database that maps changes in gene expression in the prefrontal cortex shows that autism-linked genes are expressed differently than other genes through six stages of life.

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November 2014

In autism, RNA snippets vary little by brain region, age

by  /  20 November 2014

The expression patterns of microRNAs vary less by brain region and age in people with autism than in controls. Researchers presented the unpublished findings Tuesday at the 2014 Society for Neuroscience annual meeting in Washington, D.C.

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May 2014

Genetics: Extra copy of Rett gene blocks neuron growth

by  /  20 May 2014

Having one too many copies of MeCP2, the Rett syndrome gene, may block the growth of neuronal branches by interfering with the production of small pieces of RNA, according to a study published 10 March in Developmental Cell.

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March 2014

Genetics: MicroRNA may suppress autism gene expression

by  /  25 March 2014

A small fragment of RNA may regulate the expression of RORA, a gene implicated in many autism-related pathways, according to a study published 6 February in Scientific Reports.

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No longer junk: Role of long noncoding RNAs in autism risk

by ,  /  4 March 2014

Long pieces of RNA that do not code for protein have diverse and important roles in the cell and may contribute to autism risk, say Nikolaos Mellios and Mriganka Sur.

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November 2013

RNA bits vary in social, auditory brain areas in autism

by  /  14 November 2013

People with autism show differences from controls in the levels of microRNAs, small noncoding bits of RNA, in the social and sound-processing parts of the brain. Unpublished results from the postmortem study were presented Wednesday at the 2013 Society for Neuroscience annual meeting in San Diego.

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July 2013

Fuzzy network

by  /  5 July 2013

A new network analysis of autism genes, published 11 June in Translational Psychiatry, highlights both the pitfalls and the promise of the approach, says Alan Packer.
 

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May 2013

Small pieces of RNA may pave path to autism

by  /  21 May 2013

The discovery of microRNAs that regulate gene expression has changed our view of cellular biochemistry. It may also change our perception of neuropsychiatric disorders such as autism, says Peng Jin.

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April 2013

Genetics: Regulatory RNAs found in autism risk regions

by  /  16 April 2013

Chromosomal duplications or deletions may influence autism-linked genes indirectly, by altering fragments of RNA that regulate gene expression, according to a study published 25 February in PLoS One. 

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