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Spectrum: Autism Research News

Tag: microglia

November 2013

Beth Stevens discusses brain immunity and wiring

 /  20 November 2013

Watch the complete replay of Beth Stevens discussing the link between immune cells in the brain, neuronal junctions and autism. Submit follow-up questions.

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September 2013

Duplication of chromosome 15 region mirrors autism

by  /  23 September 2013

People with autism and those with duplications of the 15q11-13 chromosomal region share a distinctive pattern of gene expression in the brain, according to unpublished research presented Friday at the Dup15q Alliance Scientific Meeting in Sacramento, California.

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August 2013

Abnormal brain immune cells: Autism’s cause or result?

by  /  19 August 2013

Mounting evidence finds abnormally high levels of immune cells in the brains of people with autism. But how do we separate cause from effect?

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Brain’s immune cells show intriguing links to autism

by  /  13 August 2013

Emerging evidence indicates that microglia, the brain’s immune cells, are altered in some individuals with autism, raising questions about their role in brain development, says Beth Stevens.

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March 2013

Jonathan Kipnis on microglia and therapeutic targets

 /  27 March 2013

Watch the complete replay of Jonathan Kipnis discussing his groundbreaking work connecting microglia and peripheral immunity to autism. Submit your own follow-up questions.

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What does the brain’s immunity have to do with autism?

by  /  4 March 2013

In December, SFARI brought together a group of scientists studying the connection between microglia and autism. These scientists are trying to delineate the next steps for this emerging field. Join the conversation.

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January 2013

Brain imaging study points to microglia as autism biomarker

by  /  10 January 2013

Microglia, brain cells that are part of the immune system, are more activated in the brains of young men with autism than in controls, according to an imaging study published 26 November in the Archives of General Psychiatry.

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Molecular mechanisms: Immune soldiers elevated in autism

by  /  4 January 2013

Children with autism have higher levels than controls of dendritic cells, a subset of immune cells, according to a study published 11 October in Brain Behavior and Immunity.

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December 2012

Molecular mechanisms: Star cells abnormal in autism brains

by  /  7 December 2012

Postmortem brains from individuals with autism have astrocytes that are smaller but denser than in control brains, according to a study published 21 September in the Journal of Neuroinflammation. The researchers found similar alterations in a mouse that lacks the autism-linked gene NLGN3.

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October 2012

‘Spiny mice’ model risk of autism from maternal infection

by  /  10 October 2012

The so-called ‘spiny mouse’ species has a gestational period twice as long as that of typical laboratory mice. This makes them good models for studying the link between prenatal exposure and autism risk, according to a study published 29 August in Brain, Behavior and Immunity.

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