Some of our favorite stories this year went beyond the news to lay bare critical controversies or highlight real-world implications of research.
Spectrum: Autism Research News
Tiny pulses of blue light dampen the expression of inflammatory genes in microglia, and may cause unplanned effects when using optogenetics.
A new study casts brain cells called astrocytes as minor stars in Rett syndrome, a disorder that almost exclusively affects girls.
Beth Stevens is unmasking new roles for microglia, the mysterious brain cells that seem to shape brain circuits.
Researchers from four labs were unable to reproduce the findings from a high-profile 2012 study in which bone marrow transplants dramatically extended the lives of mice with features of Rett syndrome. Their sobering findings were published yesterday in Nature.
An analysis of genes expressed in the postmortem brains of people with autism has identified three molecular pathways linked to the disorder. The findings, published 10 December in Nature Communications, add to mounting evidence that the myriad causes of autism converge on common biological processes.
A new study points to a possible link between inflammation in the womb, brain overgrowth and the behavioral impairments seen in autism.
Loss of MeCP2, the Rett syndrome gene, depletes immune cells throughout the bodies of mice, researchers reported yesterday at the 2014 Society for Neuroscience annual meeting in Washington, D.C.