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Tag: microglia

July 2020
Man working from home office.
News

INSAR 2020, from home

by  /  31 July 2020

Like so many other events this year, autism’s biggest annual conference — the International Society for Autism Research meeting — was forced to go virtual because of the coronavirus pandemic.

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May 2020
News

Extra proteins alter microglia and behavior in mice

by  /  29 May 2020

The overproduction of proteins in brain cells called microglia causes social impairments, cognitive deficits and repetitive behavior in male mice, a new study has found.

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November 2019
Micrograph of mouse brain showing transplanted human microglia
News / Toolbox

Chimeric mouse model aids study of brain’s immune cells

by  /  15 November 2019

A new technique allows researchers to transplant human microglia into mouse brains and better study the association between these cells and autism.

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September 2019
colorful clusters of cells
News / Toolbox

Atlas of developing brain reveals rainbow of cell types

by  /  20 September 2019

An online resource reveals all major cell types in the developing human brain during the period in which autism is thought to arise.

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May 2019
Individual cells from the brains of autistic people show distinct gene-expression patterns, and are shown in different colors.
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Analysis of single cells implicates set of neurons in autism

by  /  22 May 2019

A set of neurons involved in complex cognitive functions may play a central role in autism.

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neurons in mice brains
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Inflammation may wield sex-specific effects on developing brain

by  /  8 May 2019

Exposure to inflammation in the womb may affect the brain and behavior of males and females differently.

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December 2018
News

Massive analysis refines map of autism’s genetic roots

by  /  19 December 2018

The largest genetic analysis of postmortem brain tissue to date has yielded maps of when and where genes related to autism are turned on and off throughout life.

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November 2018
News

Neuron tag may shield synapses from brain’s pruning shears

by  /  12 November 2018

A protective molecular tag on neurons can prevent microglia, the brain’s immune cells, from trimming away their connections with other neurons.

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News

Inflammation in womb may spawn autism-like traits in males

by  /  6 November 2018

Chronic exposure to inflammation in the womb alters autism gene expression and disrupts social behavior in male mice, but not females.

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News

Postmortem brain study hints at cell types involved in autism

by  /  5 November 2018

An unprecedented look at gene expression in tens of thousands of brain cells from autistic people suggests important roles in the condition for a neuronal subtype and for microglia.

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