Alterations in inhibitory circuits and difficulties in social recognition characterize mice missing one copy of DYRK1A, a gene linked to autism.
Spectrum: Autism Research News
Mice missing the autism-linked SHANK2 and SHANK3 genes in their retrosplenial cortex have trouble distinguishing between novel and familiar mice.
Null and replicated results in this month’s newsletter tackle aging, a purported pathway for oxytocin’s effects on autistic people, and a possible autism biomarker.
In this edition of Null and Noteworthy, a large clinical trial goes sideways, while memory and emotions hold up.
In this edition of Null and Noteworthy, researchers replicate encouraging findings on autism and aging and shoot down a host of potential links between pregnancy complications and having a child with autism.
An atypical thalamus may underlie not only sensory issues in autism but also difficulties with social skills, attention and memory.
Mice with autism- or schizophrenia-linked mutations only in the anterodorsal thalamus have problems with long-term and working memory.
Over the course of a career spanning more than three decades, Huda Zoghbi has won almost every major biology and neuroscience research award that exists. More than 20 years since she discovered the gene behind Rett syndrome, she remains laser focused on unlocking the condition’s secrets and finding effective treatments.