New treatment for Rett syndrome targets cerebrospinal fluid
Lowering the levels of OTX2, a protein found in the fluid that bathes the brain, prevents many abnormal behaviors in mouse models of Rett syndrome.
Lowering the levels of OTX2, a protein found in the fluid that bathes the brain, prevents many abnormal behaviors in mouse models of Rett syndrome.
Contrary to some previous reports, microglia may not play a central role in initiating Rett syndrome.
Mice with either too little or too much MeCP2, the gene mutated in Rett syndrome, show similar malfunctions in a learning and memory circuit.
Manipulating MeCP2, the gene mutated in Rett syndrome, has revealed two neuron types as crucial contributors to the condition.
The popular gene-editing tool CRISPR can tag proteins in the brain, illuminating the whereabouts of autism candidates.
Each of the various breathing difficulties seen in people with Rett syndrome may arise from a distinct circuit in the brainstem.
The anxiety and trouble with social skills seen in people with autism may originate outside of the brain, in neurons that govern touch.
Researchers are proposing an ‘international brain station’ to share data between labs, China is becoming the destination for primate research, and 1 in 25 papers contains inappropriately copied images.
MeCP2, a gene associated with neurodevelopmental conditions such as Rett syndrome and autism, has an unexpectedly essential role in mature brains.
Headlines about “autistic monkeys” are missing the point, prairie voles show empathy, and dogs could offer clues to psychiatric conditions in people.