An experimental drug tamps down the expression of a gene duplicated in an autism-related condition and restores typical behavior in mice.
Researchers have used the gene-editing tool CRISPR to disable the MECP2 gene in marmoset embryos. The six such marmosets created seem to recapitulate aspects of Rett syndrome.
Heart-rate patterns and changes in pupil size may herald Rett syndrome, autism or related conditions.
An experimental leukemia drug and a chemical in black pepper ease breathing and movement problems in a mouse model of Rett syndrome.
Problems with protein-filled parcels called exosomes may contribute to Rett syndrome, a condition related to autism.
Brain organoids made from typical human stem cells begin to show synchronized neuronal firing patterns after growing in a dish for at least four months.
Alysson Muotri aims to build a ‘thinking’ brain as a model for autism — even if his colleagues consider that work controversial.
Brain tissues from people with autism of unknown cause and from people with either of two genetic forms of the condition all show similar patterns of methyl groups on DNA.
A cache of about 100 brain organoids grown from human cells is expected to launch into orbit this month.