Tag: MECP2

October 2019
micrographs of brain areas in red.
News

Drug counteracts effects of doubled autism gene

by  /  24 October 2019

An experimental drug tamps down the expression of a gene duplicated in an autism-related condition and restores typical behavior in mice.

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News

Gene-edited marmosets may mimic Rett syndrome traits

by  /  23 October 2019

Researchers have used the gene-editing tool CRISPR to disable the MECP2 gene in marmoset embryos. The six such marmosets created seem to recapitulate aspects of Rett syndrome.

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linked hands in a pattern intertwined with DNA showing some broken parts, symbolizing mutations
News

Rett syndrome’s link to autism, explained

by  /  21 October 2019

Studies of Rett syndrome hint at genes, cells and brain circuits that may be involved in autism — and may pave the way to treatments for both conditions.

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September 2019
white mouse on a green activity wheel
News

Patterns in heart rate, pupil size may predict Rett syndrome

by  /  18 September 2019

Heart-rate patterns and changes in pupil size may herald Rett syndrome, autism or related conditions.

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triangle effect digital rendering shows the shapes of a red neuron network
News

Drug screen reveals potential treatments for Rett syndrome

by  /  11 September 2019

An experimental leukemia drug and a chemical in black pepper ease breathing and movement problems in a mouse model of Rett syndrome.

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News

Protein ‘bubbles’ released from neurons may play role in autism

by  /  4 September 2019

Problems with protein-filled parcels called exosomes may contribute to Rett syndrome, a condition related to autism.

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August 2019
News

Brain organoids show realistic neuronal firing rhythms

by  /  29 August 2019

Brain organoids made from typical human stem cells begin to show synchronized neuronal firing patterns after growing in a dish for at least four months.

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Portrait of scientist Alysson Muotri
News / Profiles

Autism researcher Alysson Muotri’s audacious plans for brain organoids

by  /  12 August 2019

Alysson Muotri aims to build a ‘thinking’ brain as a model for autism — even if his colleagues consider that work controversial.

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July 2019
Orange patterns are created from chemical tags in brain tissue from people with autism.
News

Different forms of autism may share pattern of chemical tags on DNA

by  /  22 July 2019

Brain tissues from people with autism of unknown cause and from people with either of two genetic forms of the condition all show similar patterns of methyl groups on DNA.

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News

First brain organoids get set to travel into space

by  /  8 July 2019

A cache of about 100 brain organoids grown from human cells is expected to launch into orbit this month.

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