Tag: macrocephaly

May 2012
News

In autism, head growth patterns vary by gender

by  /  24 May 2012

Girls diagnosed with autism have slower brain growth in the first year of their life than typically developing children, whereas boys’ brains grow at the same rate as those of typical children, according to a population-based study in Norway.

0 Comments
News

Fish study links chromosome 16 genes to head size

by  /  17 May 2012

By creating genetically engineered fish, two independent groups have identified genes in an autism hotspot on chromosome 16 that influence head size and brain development. 

0 Comments
March 2012
News

Cognition and behavior: Brain changes tied to autism severity

by  /  16 March 2012

Adults with autism have regional differences in brain volume in areas that play a role in social behavior and communication compared with controls, according to a large study published in the February issue of Archives of General Psychiatry. The differences correlate with the severity of autism symptoms, the study also shows.

0 Comments
Opinion / Viewpoint

RAS pathway, a potentially unifying theory of autism

by  /  13 March 2012

Dysregulation of the intracellular signaling pathway RAS, a risk factor for idiopathic autism, may provide a unifying theory of the disorder. Although this is not an altogether new hypothesis, several new findings have strengthened the evidence for it considerably.

1 Comment
December 2011
News

Study links brain size to regressive autism

by  /  12 December 2011

Larger brains may be associated with regressive autism, but only in boys, according to a study published online 28 November in the Proceedings of the National Academy of Sciences.

5 Comments
November 2011
News

Clinical research: Toddlers with autism larger than peers

by  /  23 November 2011

Toddlers with autism who have larger-than-normal heads are also taller and weigh more than controls, according to a study published in October in Archives of General Psychiatry.

0 Comments
News

Autism brains have too many neurons, study suggests

by  /  10 November 2011

Children with autism have an abnormally large number of neurons in the prefrontal cortex, a brain region important for abstract thinking, planning and social behaviors, according to a study published yesterday in the Journal of the American Medical Association.

4 Comments
October 2011
News

Cognition and behavior: Autism brains similar in girls and boys

by  /  11 October 2011

Girls with autism have more brain matter than do either controls or girls with developmental disabilities. This defect is particularly pronounced in the left superior frontal gyrus, a region in the medial prefrontal cortex that is responsible for higher-order cognitive function.

0 Comments
Opinion / Viewpoint

Dysmorphology as biomarker for the study of autism

by  /  11 October 2011

Individuals who have autism and dysmorphology comprise a distinct subgroup within the disorder, says geneticist Judith Miles. 

2 Comments
September 2011
Opinion / Viewpoint

Insights for autism from Charcot-Marie-Tooth disease

by  /  27 September 2011

Charcot-Marie-Tooth disease and autism are both associated with alterations in the number of copies of certain genetic regions, mutations in multiple candidate genes and with both inherited and spontaneous mutations, notes human geneticist James Lupski.

2 Comments