Autism’s genetic heterogeneity evident in brain connectivity patterns
The results highlight the importance of subgrouping study participants based on their underlying genetics, the researchers say.
The results highlight the importance of subgrouping study participants based on their underlying genetics, the researchers say.
People who have ‘profound autism’ — those with severe intellectual disability, limited communication abilities or both — tend to be excluded from research. The Autism Science Foundation seeks to change that.
Almost 60 percent of autistic people may have an average or above-average intelligence quotient, according to a new longitudinal study.
Some types of restricted and repetitive behaviors become more prevalent among autistic children and teenagers over time, depending on their age and intellectual ability, whereas others decrease.
Researchers can roughly project what autistic children’s lives will look like years down the road. But how good is their crystal ball — and what are its benefits?
Cross-species comparisons can help make sense of subtle genetic variants in people with autism and identify hundreds of new genes that may contribute to the condition.
A new protocol aims to help researchers include more autistic people — especially those who are minimally verbal or have intellectual disability — in imaging studies.
There is not yet a single example of a gene that, when mutated, increases the likelihood of autism but not of other neurodevelopmental conditions, including intellectual disability.
People with mutations in distant chromosomal regions often share a range of autism traits, even if they do not meet the diagnostic threshold for autism.
The Spectrum team highlights five topics that distinguished autism research in 2020: diversity in data, gene therapies, subtyping, social circuitry and the ‘autism gene’ debate.