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Tag: ion channels

July 2012
Opinion / Viewpoint

Targeting brain microcircuits may help treat autism

by  /  10 July 2012

Understanding the function of neuronal circuits, specifically microcircuits in the prefrontal cortex and elsewhere in the brain, will play a major role in translating research findings into new autism treatments, says Vikaas Sohal.

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June 2012
News / Toolbox

Radio waves turn on gene expression

by  /  6 June 2012

The heat produced by radio waves can interact with metallic nanoparticles bound to temperature-sensitive ion channels in cells, allowing researchers to remotely alter gene expression in live animals, according to a study published 4 May in Science. The technique could also be used to activate neuronal signals by manipulating calcium influx into neurons, the researchers say. 

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May 2012
News / Toolbox

Robot replaces neuroscientists in technique

by  /  23 May 2012

A robot can replace researchers in performing a painstaking technique that records neuronal signals in live animal brains, according to a study published 6 May in Nature Methods.

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December 2011
News

Neurons made from stem cells reveal cellular flaws in autism

by  /  8 December 2011

Researchers have uncovered cellular abnormalities in Timothy syndrome by regenerating neurons from individuals with the rare autism-related disorder, according to a study published 27 November in Nature Medicine.

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November 2011
News

Researchers unveil seven new rat models of autism

by  /  16 November 2011

A large scientific research company debuted seven new rat models of autism Tuesday evening in Washington, D.C. Two of the models, one lacking FMR1 and the other lacking NLGN3, show some unexpected new characteristics.

2 Comments
News

Genetics: Middle East study tags intellectual disability genes

by  /  15 November 2011

By focusing on recessive mutations inherited from both parents, researchers have identified 50 new candidate genes for intellectual disability.

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September 2011
News

Autism exome study pinpoints mutations in brain genes

by  /  14 September 2011

Children with autism carry many more spontaneous point mutations in genes expressed in the brain compared with their unaffected siblings, according to unpublished findings presented Monday at the World Congress of Psychiatric Genetics in Washington, D.C.

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News

First mouse model of Timothy syndrome debuts

by  /  5 September 2011

Researchers have created the first mouse model of Timothy syndrome, a rare genetic disorder that causes heart defects and autism. The findings appeared 30 August in the Proceedings of the National Academy of Sciences.

7 Comments
August 2011
News / Toolbox

Modified stem cells make glowing neurons

by  /  10 August 2011

A new technique allows researchers to make stable modifications to neurons by incorporating modified amino acids into the proteins of stem cells. The method permits researchers to investigate neuronal function in live, intact cells.

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May 2011
News

Molecular mechanisms: Gene linked to autism and epilepsy

by  /  25 May 2011

Harmful mutations in a gene that regulates the chemical environment outside of neurons are associated with both autism and epilepsy, according to a study published 31 March in Neurobiology of Disease.

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