Tag: ion channels

January 2013
Opinion / Viewpoint

Exploring enigmatic links between mitochondria and autism

by  /  8 January 2013

Mitochondrial deficits may account for the range of symptoms and neurological deficits seen in autism and explain why it preferentially affects boys, says Douglas Wallace.

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November 2012
News

Molecular mechanisms: Autism protein connects neurons

by  /  28 November 2012

An autism-linked protein called CASPR2 promotes the development of dendrites, the bushy structures atop neurons that receive signals from other neurons, according to a study published 30 October in Proceedings of the National Academy of Sciences. Lowering CASPR2 levels leads to sparse dendrites and few synapses, the junctions between neurons.

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September 2012
News

Genetics: Chromosomal syndrome narrowed to single gene

by  /  11 September 2012

Symptoms associated with a deletion of the 15q13.3 chromosomal region could result from the loss of a single gene, CHRNA7, according to a study published 9 July in Clinical Genetics.

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August 2012
News

Epilepsy drug reverses autism-like symptoms in mice

by  /  27 August 2012

Researchers have homed in on the brain region thought to be responsible for the autism-like symptoms that can accompany Dravet syndrome, a rare epilepsy disorder, according to research published Wednesday in Nature.

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News / Toolbox

Choice of light-sensitive channel alters inhibitory signals

by  /  1 August 2012

An innovative technique that uses waves of light to silence brain signaling in live animals can affect subsequent neuronal signals, according to a study published 24 June in Nature Neuroscience.

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July 2012
Opinion / Viewpoint

Targeting brain microcircuits may help treat autism

by  /  10 July 2012

Understanding the function of neuronal circuits, specifically microcircuits in the prefrontal cortex and elsewhere in the brain, will play a major role in translating research findings into new autism treatments, says Vikaas Sohal.

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June 2012
News / Toolbox

Radio waves turn on gene expression

by  /  6 June 2012

The heat produced by radio waves can interact with metallic nanoparticles bound to temperature-sensitive ion channels in cells, allowing researchers to remotely alter gene expression in live animals, according to a study published 4 May in Science. The technique could also be used to activate neuronal signals by manipulating calcium influx into neurons, the researchers say. 

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May 2012
News / Toolbox

Robot replaces neuroscientists in technique

by  /  23 May 2012

A robot can replace researchers in performing a painstaking technique that records neuronal signals in live animal brains, according to a study published 6 May in Nature Methods.

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December 2011
News

Neurons made from stem cells reveal cellular flaws in autism

by  /  8 December 2011

Researchers have uncovered cellular abnormalities in Timothy syndrome by regenerating neurons from individuals with the rare autism-related disorder, according to a study published 27 November in Nature Medicine.

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November 2011
News

Researchers unveil seven new rat models of autism

by  /  16 November 2011

A large scientific research company debuted seven new rat models of autism Tuesday evening in Washington, D.C. Two of the models, one lacking FMR1 and the other lacking NLGN3, show some unexpected new characteristics.

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