Tag: ion channels

March 2014
Opinion / Viewpoint

No longer junk: Role of long noncoding RNAs in autism risk

by ,  /  4 March 2014

Long pieces of RNA that do not code for protein have diverse and important roles in the cell and may contribute to autism risk, say Nikolaos Mellios and Mriganka Sur.

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November 2013
News

Molecular mechanisms: Autism mutation dulls neurons

by  /  19 November 2013

Loss of one copy of the autism-linked gene PTEN in mouse neurons boosts production of a certain ion channel, and decreases the neurons’ firing rate, according to a study published 21 October in Proceedings of the National Academy of Sciences.

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October 2013
News

Molecular mechanisms: Study ties growth factor to autism

by  /  22 October 2013

Mutations in the autism-linked protein NHE6 may block the development of neuronal junctions by interfering with a growth factor called BDNF, according to a study published 2 October in Neuron.

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August 2013
News

New resource catalogs RNA-binding sites of many proteins

by  /  12 August 2013

A new online database lists the likely RNA-binding sites of more than 8,000 proteins from 289 species. Researchers debuted the resource in the 11 July issue of Nature.

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March 2013
Opinion / Viewpoint

Rho family of enzymes at crossroads of autism

by  /  12 March 2013

A number of autism risk factors converge on one cellular pathway: abnormal remodeling of the cell’s structural systems through the signaling protein Rho, says SFARI’s associate director for research, Alan Packer.

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News

Molecular mechanisms: Timothy syndrome neurons defective

by  /  12 March 2013

Neurons from people with Timothy syndrome, and from mouse and rat models of the disorder, have defects in the growth of their branches, according to a study published 13 January in Nature Neuroscience.

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February 2013
News / Toolbox

Scientists follow brain activity as fish find their dinner

by  /  27 February 2013

Using a sensitive new imaging molecule, researchers can watch neurons in the larval zebrafish brain spring into action when the fish sees a potential meal, according to a study published 29 January in Current Biology.

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News

Genetics: Double hit of risk genes recurrent in autism

by  /  26 February 2013

A boy with autism lacks one copy of SHANK2 and has a duplication of CHRNA7, two genes that have been linked together to autism risk, according to a case study published 25 January in Clinical Genetics.

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News

Controversial study touts blood pressure drug for autism

by  /  18 February 2013

Bumetanide, a drug that’s long been used to treat high blood pressure, modestly improves social behaviors in children with mild forms of autism, according to the results of a small trial published in December in Translational Psychiatry.

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January 2013
News / Toolbox

Mouse stem cells enable study of Rett syndrome

by  /  23 January 2013

Researchers have made neurons from the skin cells of mice that model Rett syndrome, according to a study published in the December issue Molecular Psychiatry.

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