Tag: ion channels

April 2016

Mouse study links gene to some autism symptoms

by  /  22 April 2016

Mice missing a gene called PTCHD1 in a deep-seated brain structure have autism-like symptoms that ease with treatment.

February 2016
News / Toolbox

Multipurpose tool paints three-layer portraits of neurons

by  /  3 February 2016

A new tool allows researchers to simultaneously study the physical, genetic and electrical properties of individual neurons.

November 2015
News / Toolbox

Sensitive, superfast sensor detects brain activity in real time

by  /  25 November 2015

A new tool marries an unusually bright fluorescent protein to a light-sensitive pigment to illuminate individual neurons as they fire.

September 2015
Features / Deep Dive

Magnetic promise: Can brain stimulation treat autism?

by  /  23 September 2015

There are hints that transcranial magnetic stimulation, which uses electricity to change how brain cells function, might improve the symptoms of autism. But hopes are running way ahead of the facts.

January 2015

‘Tooth Fairy’ works magic to unearth new autism genes

by  /  12 January 2015

By analyzing stem cells derived from baby teeth, researchers have tracked a child’s autism to mutations in a gene called TRPC6. The molecular saga highlights a painless way to probe the role some genes play in autism.

November 2014

Mystery gene uncovered in autism studies may steer neurons

by  /  26 November 2014

1 Comment
July 2014
Opinion / Viewpoint

Schizophrenia milestone holds lessons for autism

by  /  21 July 2014

A long-awaited report, published today in Nature, confirms that with access to tens of thousands of genomes, researchers can identify common genetic risk factors for a complex neuropsychiatric disorder.

1 Comment
May 2014
Opinion / Viewpoint

Signaling pathways link autism, schizophrenia

by  /  27 May 2014

Autism, schizophrenia and intellectual disability share underlying deficits in pathways that regulate how the brain encodes new experiences, says Jason Shepherd.

March 2014
Opinion / Viewpoint

No longer junk: Role of long noncoding RNAs in autism risk

by ,  /  4 March 2014

Long pieces of RNA that do not code for protein have diverse and important roles in the cell and may contribute to autism risk, say Nikolaos Mellios and Mriganka Sur.

November 2013

Molecular mechanisms: Autism mutation dulls neurons

by  /  19 November 2013

Loss of one copy of the autism-linked gene PTEN in mouse neurons boosts production of a certain ion channel, and decreases the neurons’ firing rate, according to a study published 21 October in Proceedings of the National Academy of Sciences.