Tag: interneurons

April 2011
News

Specialized neurons help explore circuit defects in autism

by  /  14 April 2011

A powerful cell that dampens electrical signaling in the brain could help unravel the disrupted brain wiring seen in people with autism, according to results presented yesterday at the Wiring the Brain meeting in Ireland.

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March 2011
News

Molecular mechanisms: Neuroligin-4 induces synapses in a dish

by  /  23 March 2011

Neuroligin-4, a protein associated with autism, is located at synapses — the junctions between neurons — that inhibit signals in the brain, according to a study published in February in the Proceedings of the National Academy of Sciences. The protein can also single-handedly induce neurons derived from human stem cells to form synapses, according to another study in the same issue.

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January 2011
News

Genetics: Rare mutation found in gene linked to autism

by  /  31 January 2011

Researchers have identified a rare genetic variant linked to autism in DLX1, a gene that regulates the growth of neurons, they reported in December in the American Journal of Medical Genetics.

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November 2010
News

Autism brains characterized by fewer excitatory neurons

by  /  16 November 2010

People with autism have structural differences in the temporal cortex — a brain region involved in sound and language processing — compared with controls, according to a postmortem study presented Monday at the Society for Neuroscience annual meeting in San Diego.

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News

Researchers debut new mouse model for Rett syndrome

by  /  11 November 2010

A new mouse model for Rett syndrome shows that disrupting a single brain messenger can produce nearly all of the characteristic features of the syndrome, researchers report today in Nature.

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October 2010
News

Molecular mechanisms: Calming neurons have specific responses

by  /  26 October 2010

Most inhibitory neurons respond in the same way to a range of visual stimulation, but a subset of them may be tuned in to specific signals, suggest two reports published in September in Neuron.

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March 2010
Opinion

Learning opportunities

by  /  23 March 2010

There are several short periods during development in which our brains are ‘plastic’ — meaning that neuronal connections appear and disappear depending on how much they are used. Researchers may have found a way to reopen those learning windows.

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News

Postmortem brains point to impaired inhibition in autism

by  /  4 March 2010

Researchers have found a higher density of several types of interneurons — nerve cells that connect sensory and motor neurons in the brain— in postmortem brain tissue from individuals with autism, compared with healthy controls. The findings appear in the February issue of Acta Neurologica Scandinavica.

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November 2009
News

Loss of inhibitory neurons marks autism mouse models

by  /  24 November 2009

Autism may be the result of faulty wiring that occurs during early brain development, according to two independent studies that looked at the origins of circuit disruption.

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October 2009
News

Mounting evidence links language pathway to autism

by  /  26 October 2009

A pathway involved in language development is increasingly proving to be important in autism, suggest a series of new studies on cellular and behavioral aspects of the disorder.

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