Tag: interneurons

March 2014
Opinion / Viewpoint

No longer junk: Role of long noncoding RNAs in autism risk

by ,  /  4 March 2014

Long pieces of RNA that do not code for protein have diverse and important roles in the cell and may contribute to autism risk, say Nikolaos Mellios and Mriganka Sur.

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February 2014
News / Toolbox

Gene expression implicates inhibitory neurons in autism

by  /  26 February 2014

By matching the genes expressed in particular cell types with those linked to a disorder, researchers may be able to identify the cell types implicated in the disorder, they report in a study published 22 January in the Journal of Neuroscience. They use this method to link interneurons and immune cells to autism.

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January 2014
News

Molecular mechanisms: Reward affects motor function in Rett

by  /  10 January 2014

The motor problems seen in Rett syndrome may be the result of deficits in a reward pathway in the striatum, according to a study published 12 November in Brain Structure and Function. 

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December 2013
Opinion / Viewpoint

Understanding contradictory connectivity reports in autism

by ,  /  10 December 2013

Studies at the level of neural circuits are needed to better understand the importance of both increased and decreased connectivity between different regions in the autism brain, say John Rubenstein and Vikaas Sohal.

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September 2013
News

Molecular mechanisms: Oxytocin boosts brain signals

by  /  10 September 2013

Oxytocin may enhance brain signaling by increasing the strength of the signals and minimizing background noise, according to a study published 4 August in Nature.

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June 2013
News

Molecular mechanisms: Mutations link mood system to autism

by  /  4 June 2013

Two different autism-linked mutations in the same gene implicate the endocannabinoid system, which regulates appetite, mood and memory, in autism, according to a study published 8 May in Neuron.

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March 2013
News

Molecular mechanisms: Deletion moves inhibitory neurons

by  /  1 March 2013

Loss of one copy of 22q11.2 — a chromosomal region linked to schizophrenia and autism — shifts the location of neurons that inhibit brain signals, according to a study published 6 November in Proceedings of the National Academy of Sciences.

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November 2012
News

Molecular mechanisms: Autism gene regulates brain structure

by  /  30 November 2012

Loss of one copy of TBR1, an autism-linked gene involved in fetal brain development, leads to brain malformations, according to a study published in the September issue of Molecular Syndromology.

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Opinion / Viewpoint

Insights for autism from schizophrenia

by ,  /  13 November 2012

Lessons learned from postmortem studies of schizophrenia are applicable to research on autism, a disorder for which brain tissue has not been as well studied, say Allison Curley and David Lewis.

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September 2012
News / Toolbox

Device helps record neuronal activity in moving rats

by  /  5 September 2012

A new device allows researchers to identify the precise source of an emitted brain signal measured in freely moving rats, according to a study published in the July issue of the Journal of Neurophysiology.

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