Skip to main content

Spectrum: Autism Research News

Tag: intellectual disability

April 2021
Child in an MEG machine

Making neuroimaging accessible for more autistic children

by  /  6 April 2021

A new protocol aims to help researchers include more autistic people — especially those who are minimally verbal or have intellectual disability — in imaging studies.

Comments
March 2021
Mouse brain neurons labeled with a genetic marker show pink on a dramatic blue background.

Early training forestalls motor, memory difficulties in mouse model of Rett syndrome

by  /  24 March 2021

Motor and memory training early in life postpones the onset of difficulties in those areas in a mouse model of Rett syndrome, and stimulating neurons involved in those skills appears to mimic the effects of training.

Comments
Brain made of DNA strands on a background of molecule shapes

There are no autism-specific genes, just brain genes

by ,  /  23 March 2021

There is not yet a single example of a gene that, when mutated, increases the likelihood of autism but not of other neurodevelopmental conditions, including intellectual disability.

Comments
Operating room scene shows baby being guided out of belly of mother during a c-section.

Cesarean delivery unlikely to sway child’s likelihood of autism

by  /  17 March 2021

Autism and other neurodevelopmental conditions are more common among children born by C-section than those delivered vaginally, but the procedure itself does not underlie the association, according to a new study.

Comments
Street view in Ricuarte, Colombia

Colombia lags behind in fragile X syndrome testing, diagnosis

by  /  10 March 2021

People with fragile X syndrome in Colombia are diagnosed at age 27, on average, according to the first study to assess diagnosis in the country. By comparison, the average age of fragile X diagnosis in the United States is younger than 4.

Comments

Broken protein bridge linked to Rett syndrome traits

by  /  1 March 2021

Altering a protein linked to Rett syndrome so that it cannot bind to a methylation tag in neurons results in Rett-like traits in mice.

Comments
February 2021
Heatmap plot showing how each genetic variant plus autism group differed.

Copy number variations linked to autism have diverse but overlapping effects

by  /  1 February 2021

People with mutations in distant chromosomal regions often share a range of autism traits, even if they do not meet the diagnostic threshold for autism.

Comments
January 2021
In cortical-striatal assembloids, striatal neurons (magenta) derived from individuals with Phelan-McDermid syndrome fire more frequently than neurons from controls.

Brain ‘assembloids’ capture circuit flaws in syndrome tied to autism

by  /  21 January 2021

Merging 3D clusters of neurons that mimic different brain regions models the atypical electrical activity seen in an autism-related condition.

Comments
DNMT3A protein attaches a methyl group tag onto the DNA base cytosine.

Autism-related conditions converge on same loss of DNA tags

by  /  20 January 2021

Mutations in the autism-linked gene DNMT3A lead to the behaviors and gene-expression changes seen in different neurodevelopmental conditions.

Comments
3D glasses viewing a group fo people.

The promise of scientific partnerships with people on the spectrum

by  /  14 January 2021

Five collaborations involving autistic scientists and experts are advancing autism research, from lending support for theories of the condition to shoring up trials of new treatments.

Comments