Intellectual disability
Autism-linked perturbations converge on cell skeleton and RNA-binding proteins
The findings solidify the idea that autism-linked mutations affect brain activity by way of several key shared mechanisms.
Autism-linked perturbations converge on cell skeleton and RNA-binding proteins
SYNGAP1 findings illuminate links between mutations, intellectual disability
New mouse models join several studies that could point to novel therapeutic approaches.
SYNGAP1 findings illuminate links between mutations, intellectual disability
Autism research hits the road
Some scientists are thinking creatively about how to collect data in flexible environments and meet communities where they’re at.
Journal club: Why do some children lose their autism diagnosis?
More than one-third of a cohort of autistic toddlers no longer meet criteria for the condition at school age, according to a new study, but the findings may not generalize because the cohort is predominantly white and affluent.
Journal club: Why do some children lose their autism diagnosis?
‘Emergent and transactional’: How Jonathan Green is rethinking autism and interventions
The experienced clinician discusses writing his recent paper, and its reception in the field.
‘Emergent and transactional’: How Jonathan Green is rethinking autism and interventions
Some who lack autism diagnosis carry variants tied to the condition
The variants are associated with slight differences in measures of intelligence, income and employment, but the relationship may not be causal.
Some who lack autism diagnosis carry variants tied to the condition
Autism’s ties to the cell skeleton
Many genes related to the condition play a role in the internal scaffolding of cells, and cytoskeletal disruptions can affect neurodevelopment and behavior.
New estimate suggests most autistic adults in England lack a formal diagnosis
The finding underscores a need for adult autism diagnostic services.
New estimate suggests most autistic adults in England lack a formal diagnosis
‘Polygenic risk scores’ for autism, explained
These scores — composite measures of a person’s autism-linked common genetic variants — cannot predict an autism diagnosis but could help researchers better understand the condition’s underlying biology.
‘Polygenic risk scores’ for autism, explained
Autism research at the crossroads
The power struggle between researchers, autistic self-advocates and parents is threatening progress across the field.
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How to explore your scientific values and develop a vision for your field
As a new professor, I was caught off guard by one part of the job: my role as an evaluator.
How to explore your scientific values and develop a vision for your field
As a new professor, I was caught off guard by one part of the job: my role as an evaluator.
What neuroscientists should know—and what they can do—about changes to BRAIN initiative funding
Many grant proposals submitted to the program in the past year are unlikely to be funded, according to people within the National Institutes of Health. But scientist advocates are reaching out to congressional representatives to try to make changes for 2025.
What neuroscientists should know—and what they can do—about changes to BRAIN initiative funding
Many grant proposals submitted to the program in the past year are unlikely to be funded, according to people within the National Institutes of Health. But scientist advocates are reaching out to congressional representatives to try to make changes for 2025.
Crowdsourcing to curb aggression in autism: Q&A with Matthew Goodwin
To accelerate the development of real-time behavioral prediction technology, a research team is sharing data and seeking new collaborators.
Crowdsourcing to curb aggression in autism: Q&A with Matthew Goodwin
To accelerate the development of real-time behavioral prediction technology, a research team is sharing data and seeking new collaborators.