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Spectrum: Autism Research News

Tag: intellectual disability

October 2013

Cancer pathway connects autism to set of rare disorders

by  /  21 October 2013

About one in four people diagnosed with a group of rare disorders have autism, according to a study published 7 October in the Journal of Medical Genetics. The disorders all affect a single cancer-related pathway, driven by a protein called RAS.


Sleep deprivation

by  /  18 October 2013

Children with autism go to sleep later, wake up earlier and have less restful sleep than other children their age, reports an 11-year study published 23 September.


Elliott Sherr: Coaching teams to tackle autism’s mysteries

by  /  10 October 2013

Elliott Sherr is unraveling the effects of genetics and brain structure in a handful of disparate disorders that each illuminates some aspect of autism.


ESSENCE: From defined categories to broad understanding

by  /  8 October 2013

Clinicians should place children under age 5 who have developmental delay into a broad diagnostic category, called ESSENCE, which may then resolve into any number of individual diagnoses over time, says Christopher Gillberg. 

September 2013

In autism-related disorders, RNA turns out to be key

by  /  26 September 2013

An enzyme that may keep RNA tangle-free as it’s translated into protein is missing in some people with schizophrenia and learning difficulties. The enzyme also cooperates with the protein missing in fragile X syndrome to bind RNA, suggesting a role in protein synthesis. That’s the upshot from two studies published in the September Nature Neuroscience.


Fragile facts

by  /  13 September 2013

Fragile X syndrome is the leading cause of inherited intellectual disability and often autism, but most people who work with special-needs children lack basic knowledge about the syndrome, according to a new study.


In autism, intellectual disability ramps up new mutations

by  /  10 September 2013

Spontaneous mutations are elevated in people with autism, but only in those who also have intellectual disability, according to unpublished data presented yesterday at a conference in Cambridge, Massachusetts. 


Intellectual disability may unmask autism symptoms

by  /  10 September 2013

The autism-like features seen in related neurological disorders may be the result of intellectual disability and not a shared underlying biology, says Alan Packer.


Genetics: MeCP2 mutations lead to variable symptoms

by  /  6 September 2013

Harmful mutations in MeCP2 don’t always lead to Rett syndrome, and the syndrome can result from mutations in other genes, according to a study published 26 June in the Journal of Molecular Diagnostics.

Conceptual visualization of DNA sequence.

Genetics: Recessive mutations may contribute to autism

by  /  3 September 2013

The genomes of people who have both autism and intellectual disability have more regions that may harbor recessive mutations than those of their unaffected siblings, according to a study published 11 July in the American Journal of Human Genetics.