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Spectrum: Autism Research News

Tag: intellectual disability

August 2014

London as a crucible for autism in the 1950s

by  /  15 August 2014

Autism pioneer Uta Frith reminisces about dramatic shifts in British researchers’ understanding of autism that effectively ended the institutionalization of children with the disorder.

July 2014

Autism gene affects brain function early in development

by  /  28 July 2014

Mutations in a gene linked to intellectual disability and sometimes autism may lead to a permanent boost in brain activity, according to a study published 18 June in Neuron.


Distinct features signal autism risk in tuberous sclerosis

by  /  7 July 2014

Children who have both the rare genetic disorder tuberous sclerosis complex and autism show a gradual drop in nonverbal intelligence between 1 and 3 years of age, according to research published 11 June in Neurology.


Cluster of symptoms reveals gene’s link to autism subtype

by  /  3 July 2014

CHD8, a gene that regulates the structure of DNA, is the closest thing so far to an ‘autism gene,’ suggests a study published today in Cell. People with mutations in this gene all have the same cluster of symptoms, including autism.

June 2014

Cognition and behavior: Motor deficits match autism severity

by  /  20 June 2014

The severity of core autism symptoms in young children goes hand in hand with the degree of the children’s difficulty with motor tasks.


Genetics: New variants linked to intellectual disability

by  /  17 June 2014

Newly discovered mutations in a gene called SETD5 caused intellectual disability and autism-like symptoms in seven children, according to a study published 3 April in The American Journal of Human Genetics.


Cognition and behavior: Seizures may spark social deficits

by  /  6 June 2014

Inducing seizures in young mice leads to autism-like social behavior, as well as problems with learning and memory, according to a paper published 29 March in Experimental Neurology.


In autism, brain shows unusual thinning throughout life

by  /  5 June 2014

The cortex, the outer layer of the brain, grows rapidly in early childhood in people with autism and thins differently with age than it does in controls, two new studies report.


Large study underscores role of gene copy number in autism

by  /  2 June 2014

People with autism tend to carry mutations that duplicate or delete several genes at once, according to a large study published 1 May in the American Journal of Human Genetics.

May 2014

Clinical research: Angelman gene variants alter symptoms

by  /  30 May 2014

The nature of the mutation that leads to Angelman syndrome — a disorder characterized by speech impairment and developmental delays — affects the disorder’s presentation, reports a study published 19 March in Research in Developmental Disabilities.