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Spectrum: Autism Research News

Tag: intellectual disability

November 2014

Treatment prevents autism-like symptoms in ‘teenage’ mice

by  /  16 November 2014

A treatment that targets the genetic defect in tuberous sclerosis prevents autism-like symptoms in mice at 6 weeks of age — the mouse equivalent of adolescence. Researchers presented the unpublished results yesterday at the 2014 Society for Neuroscience annual meeting in Washington, D.C.

October 2014

Timing between pregnancies may alter autism risk

by  /  28 October 2014

Children born too soon or too long after their siblings have an increased risk of autism, a new study reports.


Searching for psychiatrists with expertise in autism

by  /  17 October 2014

There is an urgent need for psychiatrists who are trained to care for individuals with autism. Matthew Siegel calls for a formal training program in autism for psychiatrists.

September 2014

Study uncovers link between autism risk gene, language

by  /  30 September 2014

Mutations in TBR1, a candidate gene for autism, compromise its functions and its ability to bind its partners — including FOXP2. Alan Packer explores the gene’s emerging link to language.

Mouse lab test: the three chambered assay

Optimizing behavioral assays for mouse models of autism

by  /  23 September 2014

As the number of autism rodent models climbs, it is a good time for the field to step back and consider the best practices for assessing autism-like symptoms in rodents, says Jacqueline Crawley.


SHANK3 mutations turn up in high proportion of autism cases

by  /  18 September 2014

About 2 percent of people who have both autism and intellectual disability carry harmful mutations in SHANK3, a protein that helps organize the connections between neurons, according to a study published 4 September in PLoS Genetics.


Analysis predicts odds of mutations’ link to autism

by  /  11 September 2014

A new method of statistical analysis can predict whether a rare mutation identified in someone with autism has a meaningful association with the disorder or was found only by chance, researchers reported in the September issue of Nature Genetics.

August 2014

In fragile X syndrome, coping skills decline with age

by  /  26 August 2014

As they age, children with fragile X syndrome may become worse at adapting to change, according to a study published 28 July in Pediatrics.


Autism may lower risk of childhood injuries

by  /  22 August 2014

Children with autism often appear to be clumsy, but in fact the disorder may protect them from injury, suggests a study published in the July-August issue of Academic Pediatrics.


Large genetic deletion leads to autism, but not always

by  /  21 August 2014

To characterize people who carry deletions in 16p11.2 and 15q13.3, genetic regions linked to autism, two studies published this summer looked in detail at dozens of people with either deletion. The studies found that deletions in these regions lead to diverse symptoms that only sometimes include autism.