When Van de Water isn’t busy mentoring “the next generation of scientists” in her lab, she finds time to paint, watch HGTV and hang out with her horse, Hank.
Spectrum: Autism Research News
Tag: immune system
The inflammation associated with the disease, particularly in mothers, may contribute to autism traits in children.
Having a genetic predisposition to inflammation is linked to structural changes in brain regions implicated in neurodevelopmental conditions.
Inspired by watching her autistic nephew grow up, Croen has also been an advocate for bolstering research and services for autistic adults.
Given the known link between severe maternal infections and autism, some scientists are investigating whether COVID-19 during pregnancy can affect a child’s neurodevelopment.
Activating the immune system blunts social behavior in mice missing a copy of the autism-linked gene SHANK3, according to a new study. Blocking TRPV4, which encodes an ion channel involved in inflammatory responses, can reverse this effect.
A failed replication and other problems led autism researcher Beth Stevens and her co-investigator to retract the nearly 10-year-old report.
Infection during pregnancy can tweak a mouse’s gut microbiome in ways that have lasting effects on her pups’ immune system and increase their chances of gut inflammation, a new study suggests.
Cortical organoids that contain non-neuronal brain cells called microglia may reflect human neurodevelopment more faithfully than those that don’t.
Animal models of autism rooted in exposure to maternal antibodies hint at different mechanisms.