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Spectrum: Autism Research News

Tag: immune system

November 2021

Including immune cells in brain organoids improves model’s accuracy

by  /  15 November 2021

Cortical organoids that contain non-neuronal brain cells called microglia may reflect human neurodevelopment more faithfully than those that don’t.

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Auto-antibodies shape brain development in myriad ways

by  /  8 November 2021

Animal models of autism rooted in exposure to maternal antibodies hint at different mechanisms.

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September 2021
A concerned man holds his toddler close

Severe infection may raise odds of autism in some children

by  /  17 September 2021

Mock viral infections impair social memory in mice with a mutation tied to autism, and autistic boys are more likely than their non-autistic peers to have had serious infections early in life.

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July 2021
Micrograph showing fewer neurons in fetal mice whose mothers have only one functional copy of PTEN.

Maternal genetics may contribute to autism-like traits in mice via inflammation

by  /  2 July 2021

A mouse model hints that genes linked to inflammation in some women may increase the likelihood of autism in their children.

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June 2021
Micrographs of mouse astrocytes with high levels of inflammatory molecules.

Immune-regulating cells contribute to autism-like traits in mice

by  /  21 June 2021

The link between autism and prenatal exposure to an immune response may involve altered levels of immune cells, according to a new study.

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May 2021
Microglia activity seen in red, green and blue.

Autism mutation may cause big brain via ‘don’t eat me’ signals

by  /  17 May 2021

An autism-linked mutation could make the brain grow unusually large by prompting cells to express a chemical signal better known for its connection to cancer.

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Brown rat mother and pup in rustic setting with burlap and wheat.

Maternal antibodies tied to autism bind to budding rat neurons

by  /  6 May 2021

Certain antibodies may shape neurodevelopment by attaching to and invading new neurons in the brain.

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April 2021
Baby in utero surrounded by pills, on bright blue background

The link between vitamins, supplements and autism, explained

by  /  14 April 2021

Too little — or too much — of certain substances during pregnancy may increase the odds of having a child with autism. Here we explain what scientists know about these associations.

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March 2021

Innate stress response may link maternal infection to autism

by  /  19 March 2021

A typically protective stress response could help to explain the connection between maternal illness and neurodevelopmental conditions.

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December 2020
White lab mouse sitting in a gloved hand.

Notable papers in autism research, 2020

23 December 2020

Gene therapies and the factors influencing autism traits top Spectrum’s list of the 10 most notable research findings we covered in 2020.

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