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Tag: hyperactivity

May 2012
News

Molecular mechanisms: SHANK2, SHANK3 mouse brains differ

by  /  16 May 2012

Mice lacking the autism-associated gene SHANK2 show autism-like behaviors similar to those seen in mice lacking SHANK3, another member of the same gene family. But SHANK2 and SHANK3 mice have distinct alterations at neuronal junctions, according to a report published 29 April in Nature.

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News

Better tools needed to assess clinical trials

by  /  14 May 2012

The past few years have seen an unprecedented number of clinical trials for experimental drugs to treat autism-related disorders, most notably for fragile X syndrome. But as the trials progress, scientists are calling for better methods to measure the drugs’ effectiveness.

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News

Genetics: SHANK1 mutations found in men with autism

by  /  11 May 2012

Researchers have identified deletions in SHANK1 — the third member of a gene family that is closely linked to autism — in five men with the disorder, they reported 4 May in the American Journal of Human Genetics. This is the first study linking SHANK1 mutations to people with autism.

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Opinion

Biased search

by  /  1 May 2012

Publication bias is making antidepressants look like a better option for treating autism than they really are, according to a study published last week in Pediatrics.

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April 2012
News / Toolbox

Chili pepper protein can alter behavior of mice

by  /  18 April 2012

By manipulating the location of a protein that detects capsaicin, the molecule responsible for the burn in hot chili peppers, researchers can activate subpopulations of neurons and alter the behavior of mice. The results were published 20 March in Nature Communications.

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News

Clinical research: Drug improves quality of life with autism

by  /  17 April 2012

Aripiprazole, a drug approved by the U.S. Food and Drug Administration to treat irritability in children with autism, may also improve their overall health-related quality of life, according to a retrospective analysis of two clinical trials. The results were published 21 March in Clinical Therapeutics.

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March 2012
News

Clinical research: Gut bacteria prevalent in autism

by  /  9 March 2012

A certain type of bacteria is prevalent in the intestines of children who have both autism and gastrointestinal (GI) symptoms but absent in controls, according to a study published 10 January in mBio.

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News

Clinical trials for autism treatments go online

by  /  8 March 2012

A new clinical trial, conducted entirely online, could provide a model for how to quickly and efficiently test some potential treatments for autism.

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February 2012
Opinion / Viewpoint

Insights for autism from attention deficit hyperactivity disorder

by  /  7 February 2012

Autism and attention deficit hyperactivity disorder show genetic and neurobiological overlap, which may provide clues to the origin of both disorders, says Joel Nigg.

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January 2012
News

Clinical research: Study suggests drug for fragile X syndrome

by  /  17 January 2012

A compound that boosts inhibitory signals in the brain could treat hyperactivity and excitability in mice that model fragile X syndrome, according to a study published 8 November in Developmental Neuroscience.

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