Researchers have repurposed the gene-editing tool CRISPR to dial down a gene’s activity in select subtypes of neurons in mice.

Researchers find a surprising link between certain pollutants and reduced autism risk, the world welcomes — and fears — the first primate clones, and new U.S. clinical trial rules reverberate globally.

The drug mavoglurant has no effect on a brain circuit involved in social behavior in a mouse model of fragile X syndrome. That may explain its poor performance in people with the condition.

A gene called TRIO may be a hotbed for autism mutations, an international collaboration focuses on the whole brain and one behavior, and Autism Speaks cuts grant spending.

Pups born to pregnant mice infected with a mock virus are known to show changes in their immune system. These effects may in turn impair proper brain signaling, according to results presented Saturday at the 2013 Society for Neuroscience annual meeting in San Diego.

A rare condition marked by a sudden and profound loss of skills is biologically distinct from other forms of autism.

A doctor decodes a rare genetic condition, burnout is a big problem in science, and an actor with autism will play the lead in “The Curious Incident of the Dog in the Night-Time.”

The absence of an autism-linked gene, combined with exposure to a mock infection, produces social deficits in mice — but only in males.

Mice have long been the mainstay of autism research, but a small group of scientists say rats are the superior choice. Rats are bigger, smarter, friendlier — and a lot more fun.

Researchers have engineered two new rats with mutations in a family of genes that function at neuronal junctions, they reported today at the 2014 International Meeting for Autism Research in Atlanta.