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Spectrum: Autism Research News

Tag: hippocampus

January 2021
two mice interacting.

Mice show brain, behavior changes weeks after oxytocin treatment

by  /  11 January 2021

Intranasal oxytocin may spur new neuron growth and changes in social behavior after a few weeks.

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lab mice

Mice with autism-related mutations show brain signaling imbalance

by  /  4 January 2021

Mutations in POGZ, a gene strongly linked to autism, lead to a signaling imbalance in multiple brain regions in mice, according to two new studies.

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December 2020
Micrograph of nerve cells being targeted by CRISPR enzyme to activate the silenced gene in Angelman syndrome

Hot topics in autism research, 2020

by  /  23 December 2020

The Spectrum team highlights five topics that distinguished autism research in 2020: diversity in data, gene therapies, subtyping, social circuitry and the ‘autism gene’ debate.

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Protein in brain

Drug helps mice with autism-linked mutation recognize others

by  /  21 December 2020

Mice that model 22q11.2 deletion syndrome lack social memory, but that trait can be reversed using a drug that targets the flow of potassium ions in neurons.

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October 2020
four brain areas marked with flags: Cortex, amygdala, hippocampus, cerebellum

Brain structure changes in autism, explained

by  /  15 October 2020

Autistic people have distinct patterns of brain development, which sometimes result in differences in brain structure. Here’s what we know about those differences.

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July 2020
Person sleeping with EEG electrodes attached to head

Losing sleep: How researchers miss a key contributor to autism

by ,  /  16 July 2020

Doctors and scientists should consider sleep problems an integral part of autism and begin to study them in more rigorous ways.

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Fine-tuning brain activity reverses memory problems in mice with autism mutation

by  /  6 July 2020

Dampening overactive brain circuits alleviates social and memory problems in a mouse model of 22q11.2 deletion syndrome.

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March 2020
Brain scans showing differences between those with TBR1 mutations and controls.

Mutations in top autism gene linked to changes in brain structure

by  /  4 March 2020

People with mutations in a gene called TBR1 have unusual features in several brain regions, along with autism traits and developmental delay.

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November 2018
Delicate network of neurons and synapses.

Webbing around neurons altered in autism mouse models

by  /  8 November 2018

Lattice-like structures that surround neurons may be overly abundant — or scarce — in brain regions of three autism mouse models.

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Two white mice, one on a wheel, sniff noses.

Infection during childhood may aggravate autism risk from mutation

by  /  7 November 2018

Triggering an immune defense in newborn male mice missing a copy of TSC2, a gene linked to autism, impairs the mice’s social memory.

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