A potential new gene therapy delivered via a single injection mimics ratios of proteins normally found in cells.
Spectrum: Autism Research News
Jolting a bundle of nerve fibers deep in the brain restores learning and memory in mice with mutations of the autism-linked gene CDKL5.
Misaligned gene expression maps suggest that some autism-linked genes play distinct roles in mouse and human brains.
Intranasal oxytocin may spur new neuron growth and changes in social behavior after a few weeks.
Mice missing a copy of the autism-linked gene NRXN1 appear to perceive some time intervals as shorter than control mice do, according to a new study.
Mutations in POGZ, a gene strongly linked to autism, lead to a signaling imbalance in multiple brain regions in mice, according to two new studies.
The Spectrum team highlights five topics that distinguished autism research in 2020: diversity in data, gene therapies, subtyping, social circuitry and the ‘autism gene’ debate.
Mice that model 22q11.2 deletion syndrome lack social memory, but that trait can be reversed using a drug that targets the flow of potassium ions in neurons.