How a ‘pacemaker’ for the brain could ease autism traits
Looking at the brain as a whole suggests that nudging flawed sets of neurons to collaborate better might alleviate autism traits.
Looking at the brain as a whole suggests that nudging flawed sets of neurons to collaborate better might alleviate autism traits.
A huge new research collaboration may jump-start the race to develop therapies for autism.
Researchers have repurposed the gene-editing tool CRISPR to dial down a gene’s activity in select subtypes of neurons in mice.
A fusion of two existing drugs alleviates autism-like features in a mouse model of the condition.
The drug mavoglurant has no effect on a brain circuit involved in social behavior in a mouse model of fragile X syndrome. That may explain its poor performance in people with the condition.
Introducing the gene UBE3A into neurons that dampen brain activity prevents seizures in a mouse model of Angelman syndrome.
A gene called TRIO may be a hotbed for autism mutations, an international collaboration focuses on the whole brain and one behavior, and Autism Speaks cuts grant spending.
Music therapy proves ineffective for autism, brain structures differ with 16p11.2 duplications and deletions, and mice missing NLGN3 may influence the sociability of their littermates.
A drug that alters the balance of two key chemical messengers in the brain may help treat autism, suggests a proof-of-principle study.
Having too many copies of an autism gene called UBE3A mutes a brain region that may mediate the satisfaction a person derives from social interactions.