How variability among mouse strains can aid autism research
Researchers can convert the distinct genetic backgrounds of lab mice from a problem to an advantage, exploiting the differences to advance our understanding of autism.
Researchers can convert the distinct genetic backgrounds of lab mice from a problem to an advantage, exploiting the differences to advance our understanding of autism.
Integrating human-specific genetic elements into mice may provide a permissive, ‘humanized’ environment for studying autism.
A semirural Colombian town called Ricaurte is home to the largest recorded genetic cluster of people with mutations linked to fragile X syndrome.
Existing genome scans do not detect many of the DNA variants that underlie behavioral problems.
After lagging behind other countries for decades, France is working on a new national plan for autism.
Two new methods allow scientists to swap single bases in DNA or RNA sequences.
More than 5 percent of mutations thought to have arisen spontaneously in a child with autism may in fact be inherited.
A cannabis gel may ease features of fragile X syndrome, omega fatty acids show promise for autism in two trials, and oxytocin reinforces social behaviors through the brain’s reward pathway.
Mutations that appear in only some of the body’s cells contribute to autism in about 4 percent of people with the condition.
Watch the complete replay of this journal club, which featured two papers on mosaic mutations in autism.