How to best use a large volume of data to discover new genetic risk factors for autism is a matter of intense debate, particularly in light of historical challenges.

Families need more support from researchers in order for their heroic efforts to be optimally effective.

Autism researchers’ top priority should be shifting their focus to finding treatments for severe forms of the condition.

Autism researchers should ditch the false dichotomy between common inherited variants and much rarer random mutations.

The landscape of chemical modifications on the DNA of people with autism could reveal clues to the condition and lead to treatments.

Teasing out how genes interact can offer clues to autism’s causes and point to treatment targets.