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Spectrum: Autism Research News

Tag: gene expression

September 2011

Genetics: Protein that regulates serotonin linked to autism

by  /  27 September 2011

A protein that regulates the development of serotonin-producing neurons in the brain is associated with autism.

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Brain activity triggers widespread epigenetic changes

by  /  26 September 2011

Methylation marks were thought to be permanent features of the genome, but a new study challenges that idea.

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Cognition and behavior: Probiotics alleviate anxiety in mice

by  /  20 September 2011

Probiotic bacteria alleviate stress in healthy mice and modify the expression of receptors for a chemical messenger that inhibits signaling in the brain.

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Researchers map gene expression in layers of mouse brain

by  /  16 September 2011

A new atlas of gene expression patterns in the adult mouse brain shows how thousands of genes are turned on in specific layers of the cortex.

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Researchers identify gene regulating amygdala volume

by  /  13 September 2011

A variant of the FGF14 gene may decrease the volume of the amygdala, a brain structure needed to interpret emotions in facial expressions, according to results presented on Sunday at the World Congress of Psychiatric Genetics in Washington, D.C.

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New mutations spike in offspring of older fathers

by  /  12 September 2011

The offspring of older male mice are 16 times more likely to harbor a spontaneous copy number variation — a deletion or duplication of genetic material — than are the offspring of young males, according to a new study.

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First mouse model of Timothy syndrome debuts

by  /  5 September 2011

Researchers have created the first mouse model of Timothy syndrome, a rare genetic disorder that causes heart defects and autism. The findings appeared 30 August in the Proceedings of the National Academy of Sciences.

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August 2011

Language gene regulates autism candidate

by  /  25 August 2011

A protein linked to language development, FOXP2, regulates the autism candidate gene MET, according to a study published 10 August in the Journal of Neuroscience.

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Attention deficit, autism share genetic risk factors

by  /  22 August 2011

Some of the same genetic risk factors may underlie both autism and attention deficit hyperactivity disorder, according to a study published 10 August in Science Translational Medicine.

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Molecular mechanisms: MeCP2 regulated by chemical switch

by  /  17 August 2011

MeCP2, the protein missing in people with Rett syndrome, enhances learning and memory by binding to key genes and either activating or inhibiting their expression, according to a study published 17 July in Nature Neuroscience. Adding a phosphate to the protein in response to neuronal activity releases MeCP2 from these genes, the study found.

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