The protein missing in fragile X syndrome is necessary for the proper development of neural stem cells — self-renewing cells that can differentiate into more specialized types, including neurons — according to a paper published in the August issue of Human Molecular Genetics.
Spectrum: Autism Research News
Tag: gene expression
The mouse brain has more than 1,300 regions for which the copy from one parent is expressed more often than the one from the other parent, according to two studies published today in Science. These so-called imprinted genes have been proposed to cause some cases of autism, but the researchers say their findings do not support that theory.
Random changes in gene expression can cause genetically identical embryos to develop different traits, according to a study of worms published in Nature. The findings suggest that haphazard movements of molecules could partly explain why autism-associated mutations don’t always cause the same symptoms.
The protein that is mutated in Rett syndrome controls the expression of other genes by changing the way DNA packs into a cell, rather than turning genes on or off, according to a study published in Molecular Cell.