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Spectrum: Autism Research News

Tag: gene expression

November 2011

Video: What is the fragile X protein’s role in a neuron?

by  /  15 November 2011

The fragile X protein FMRP helps make proteins at the synapse, the junction between neurons, even when the genetic instructions for doing so are located far away in the nucleus, says Kimberly Huber.

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New approach mines multiple sources to link genes to disease

by  /  14 November 2011

Researchers have developed a computational technique that allows them to simultaneously use multiple types of information — including gene expression, ratings and associations — to identify candidate genes for a disorder. The unpublished results were presented Sunday at the 2011 Society for Neuroscience annual meeting in Washington, D.C.

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Video: A landscape view of DNA modifications

by  /  14 November 2011

In a video interview at the 2011 Society for Neuroscience annual meeting in Washington, D.C., Janine LaSalle makes a case for the importance of the methylome in autism research.

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Subset of Rett gene’s targets may lead to the disorder

by  /  14 November 2011

Deleting the Rett syndrome gene in a subset of neurons, instead of throughout the body, dramatically lowers the number of genes that are dysregulated in those neurons, according to results presented in a poster session Saturday at the 2011 Society for Neuroscience annual meeting in Washington, D.C.

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Autism-linked protein plays role in zebra finch song

by  /  14 November 2011

Male zebra finches have high levels of contactin associated protein-like 2 (CNTNAP2), a protein that has been linked to autism and language disorders, in a key song-related area of their brains, according to unpublished research presented in a poster session Sunday at the 2011 Society for Neuroscience annual meeting in Washington, D.C.

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‘Outlier’ genes expressed differently in people with autism

by  /  13 November 2011

Individuals who have autism show distinct patterns of gene expression in neurological pathways compared with their unaffected siblings, according to unpublished work presented Saturday at the 2011 Society for Neuroscience annual meeting in Washington, D.C.

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SFN storms the capital

by  /  11 November 2011

We’re headed to Washington, D.C. for the Society for Neuroscience annual meeting, and hope to make your lives a little bit easier by reporting on what matters to you.

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SFN storms the capital

by  /  10 November 2011

We’re headed to Washington, D.C. for the Society for Neuroscience annual meeting, and hope to make your lives a little bit easier by reporting on what matters to you.

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Molecular mechanisms: MeCP2 may modify DNA structure

by  /  9 November 2011

The Rett syndrome gene MeCP2 may subtly regulate the expression of genes across the genome by altering DNA structure.

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Researchers map genetic variation in mice

by  /  9 November 2011

Researchers have sequenced 17 laboratory mice and mapped 56.7 million single-base DNA variants in their genomes, according to a study published 15 September in Nature. A companion paper in the same issue identifies more than 700,000 structural variants, which are insertions, deletions or other modifications of DNA.

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